1.4.3.14: L-lysine oxidase
This is an abbreviated version!
For detailed information about L-lysine oxidase, go to the full flat file.
Reaction
Synonyms
AIP, apoptosis-inducing protein, L-LOX/MOG, L-lysine alpha-oxidase, L-lysine oxidase/monooxygenase, L-lysine-a-oxidase, L-lysine-alpha-oxidase, L-lysyl-alpha-oxidase, L6150, LyOx, lysine-oxidase, LysOx
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Application
Application on EC 1.4.3.14 - L-lysine oxidase
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agriculture
analysis
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L-lysine-alpha-oxidase is immobilised by co-crosslinking onto the surface of a Pt electrode. The resulting amperometric biosensor is able to analyse L-lysine. The immobilised enzymes and amperometric biosensor can be used for substrate analysis and as a convenient tool for enzyme kinetic studies
medicine
nutrition
pharmacology
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the enzyme inhibits the growth of highly infectious bacterium Erwinia amylovora (causative agent of fire blight)
agriculture
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the enzyme is active towards pathogenic microorganisms, fungi, and nematodes. It exhibits inhibitory effect towards extremely hazardous Acidovorax citrulli bacterium (that causes seedling blight and bacterial fruit blotch of cucurbits)
agriculture
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the enzyme inhibits the growth of highly infectious bacterium Erwinia amylovora (causative agent of fire blight)
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agriculture
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the enzyme is active towards pathogenic microorganisms, fungi, and nematodes. It exhibits inhibitory effect towards extremely hazardous Acidovorax citrulli bacterium (that causes seedling blight and bacterial fruit blotch of cucurbits)
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medicine
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suppresses efficiently genital herpes simplex virus type II (HSV-2) infection in guinea pig, showing the best results after combined treatment with enzyme gel and intramuscular injection on day 5 postinfection
medicine
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the enzyme is an anticancer agent for the treatment of solid tumors in vivo
medicine
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the enzyme severely inhibits growth of cancer cells but shows relatively low cytotoxicity fo normal cells
medicine
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the enzyme may be used to reduce levels of L-Lys and polyamines in the brain. The enzyme enetrates into the brain and is retained there for up to 48 h after intravenous injection. The most significant impact of the enzyme is towards amino acids, which are directly exposed to its action (L-Lys, L-Orn, L-Arg). In addition, the enzyme significantly affects the redistribution of amino acids directly associated with the tricarboxylic acid cycle (L-Asp and l-Glu). The depletion of L-Orn, the precursor of polyamines, leads to a significant and long-term decrease in the concentration of polyamines, which are responsible for regulation of many processes including cell proliferation
medicine
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suppresses efficiently genital herpes simplex virus type II (HSV-2) infection in guinea pig, showing the best results after combined treatment with enzyme gel and intramuscular injection on day 5 postinfection
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medicine
Trichoderma aureoviride Rifai VKM F-4268D
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the enzyme may be used to reduce levels of L-Lys and polyamines in the brain. The enzyme enetrates into the brain and is retained there for up to 48 h after intravenous injection. The most significant impact of the enzyme is towards amino acids, which are directly exposed to its action (L-Lys, L-Orn, L-Arg). In addition, the enzyme significantly affects the redistribution of amino acids directly associated with the tricarboxylic acid cycle (L-Asp and l-Glu). The depletion of L-Orn, the precursor of polyamines, leads to a significant and long-term decrease in the concentration of polyamines, which are responsible for regulation of many processes including cell proliferation
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medicine
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the enzyme severely inhibits growth of cancer cells but shows relatively low cytotoxicity fo normal cells
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the optical enzyme sensor system with immobilized LyOx membrane can be used for rapid determination of L-Lys in a real food sample
nutrition
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the optical enzyme sensor system with immobilized LyOx membrane can be used for rapid determination of L-Lys in a real food sample
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promising enzyme for further investigation as a potential anticancer agent. Antitumor effect against murine tumors and human cancer xenografts
pharmacology
Trichoderma aureoviride Rifai VKM F-4268D
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promising enzyme for further investigation as a potential anticancer agent. Antitumor effect against murine tumors and human cancer xenografts
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