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1.4.3.13: protein-lysine 6-oxidase

This is an abbreviated version!
For detailed information about protein-lysine 6-oxidase, go to the full flat file.

Word Map on EC 1.4.3.13

Reaction

[protein]-L-lysine
+
O2
 +
H2O
=
[protein]-(S)-2-amino-6-oxohexanoate
 +
NH3
 +
H2O2

Synonyms

elastin synthetase, LO, LOR2, LOX, LOX-like 2, LOX-like 3, LOX-like protein, LOX-PP, LOXL, LOXL-2, LOXL1, LOXL1 protein, Loxl2, LOXL2a, Loxl3, LOXL3-sv1, LOXL3a, LOXL3b, LOXL4, LOXL5a, LOXL5b, lysyl oxidase, lysyl oxidase 1, lysyl oxidase 3, lysyl oxidase homolog 2, lysyl oxidase like 4, lysyl oxidase like-1, lysyl oxidase like-1 protein, lysyl oxidase propetide, lysyl oxidase-like, lysyl oxidase-like 1, lysyl oxidase-like 2, lysyl oxidase-like 2a, lysyl oxidase-like 2b, lysyl oxidase-like 3a, lysyl oxidase-like 3b, lysyl oxidase-like 4, lysyl oxidase-like 5a, lysyl oxidase-like 5b, lysyl oxidase-like protein, lysyl oxidase-like1 protein, lysyl oxidases, More, oxidase-like protein 1, PPLO, protein-6-oxidase, protein-L-lysine:oxygen 6-oxidoreductase, protein-lysine 6-oxidase, RAS excision protein, rDmLOXL-1, WS9-14

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.13 protein-lysine 6-oxidase

Cloned

Cloned on EC 1.4.3.13 - protein-lysine 6-oxidase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cloning from cDNA library, DNA and amino acid sequence determination and analysis, expression of C-terminally His6-tagged LOX in Escherichia coli
-
expressed in CHO-K1 cells
expressed in Drosophila melanogaster Schneider-2 cells
expressed in Escherichia coli
expressed in immature dendritic cells derived from peripheral blod mononuclear cells
-
expressed in MEF cells
-
expressed in NCI-H1299, NIH-3T3 and PANC-1 cells
-
expressed in RFL6 cells
-
expressed in TREX 293 cells
-
expression analysis
-
expression in Escherichia coli
expression in Escherichia coli. Heterologously expression yields an active recombinant enzyme with important biochemical features conserved
-
expression of mature enzyme and C-terminally deleted enzyme as N-terminally His6-tagged enzymes
-
expression of mature enzyme, proenzyme, and of isolated propeptide in Escherichia coli strain BL21-A1
-
expression of proenzyme, mature enzyme, isolated propeptide, and mutant enzymes in HEK-293 cells as HA-tagged proteins
-
expression of proteolytically processed forms of LOX, LOXL1, and LOXL2 in Escherichia coli as N-terminally His6-tagged proteins
-
genes and isozymes LOXL1 and LOX, detailed expression analysis in aorta during growth and development, overview
-
LOX genotyping of Asian non-areca nut chewers and arec nut chewers of different ages, overview
-
LOX propeptide is expressed in mouse mammary tumor virus Her-2/neu-driven breast cancer cell line
-
LOXL3 cDNA is expressed in human HT-1080 fibrosarcoma cells
real-time quantitative PCR enzyme expression analysis in wild-type and mutant mice
-
RT-PCR enzyme expression analysis in esophageal squamous cell carcinoma cells, overview
-