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1.4.3.12: cyclohexylamine oxidase

This is an abbreviated version!
For detailed information about cyclohexylamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.12

Reaction

Cyclohexylamine
+
O2
+
H2O
=
cyclohexanone
+
NH3
+
H2O2

Synonyms

ArCHAO, CF596_10820, chaA, CHAO, CHAOCCH12-C2

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.12 cyclohexylamine oxidase

Substrates Products

Substrates Products on EC 1.4.3.12 - cyclohexylamine oxidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1R)-1-(4-chlorophenyl)ethan-1-amine + H2O + O2
1-(4-chlorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(1R)-1-phenylethan-1-amine + H2O + O2
1-phenylacetaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(1R,2R)-2-aminocyclohexanol + O2 + H2O
cyclohexanone + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(1R,2R)-2-aminocyclopentanol + O2 + H2O
cyclopentanone + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(1R,2S)-1-amino-2-indanol + O2 + H2O
? + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(1S)-1-(4-chlorophenyl)ethan-1-amine + H2O + O2
1-(4-chlorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(1S)-1-phenylethan-1-amine + H2O + O2
1-phenylacetaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(1S)-1-phenylpropan-1-amine + H2O + O2
1-phenylpropan-1-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(1S,2R)-1-amino-2-indanol + O2 + H2O
? + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(1S,2S)-2-aminocyclohexanol + O2 + H2O
cyclohexanone + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(1S,2S)-2-aminocyclopentanol + O2 + H2O
cyclopentanone + NH3 + H2O2
show the reaction diagram
Arthrobacter sp. TYUT010-15
the enzyme shows highly R-selective deamination activity toward beta-amino alcohols
-
-
?
(2R)-heptan-2-amine + H2O + O2
heptan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(2S)-heptan-2-amine + H2O + O2
heptan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(R)-1-(4-chlorophenyl)ethylamine + O2 + H2O
1-(4-chlorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(R)-1-(4-fluorophenyl)ethanamine + O2 + H2O
1-(4-fluorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(R)-1-aminotetraline + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
(R)-2-heptylamine + O2 + H2O
heptan-2-one + NH3 + H2O2
show the reaction diagram
(S)-1-(4-chlorophenyl)ethylamine + O2 + H2O
1-(4-chlorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-1-(4-fluorophenyl)ethanamine + O2 + H2O
1-(4-fluorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-1-aminoindan + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
(S)-1-aminotetraline + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
(S)-1-aminotetraline + O2 + H2O
tetralone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-1-p-tolylethanamine + O2 + H2O
1-(4-methylphenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-1-phenylethanamine + O2 + H2O
? + NH3 + H2O2
show the reaction diagram
(S)-1-phenylethylamine + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
(S)-1-phenylpropan-1-amine + O2 + H2O
1-phenylpropionaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-2-aminohexane + O2 + H2O
hexan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
(S)-2-heptylamine + O2 + H2O
heptan-2-one + NH3 + H2O2
show the reaction diagram
-
25% activity compared to cyclohexylamine
-
-
?
(S)-alpha-methylbenzylamine + O2 + H2O
?
show the reaction diagram
-
55% activity compared to cyclohexylamine
-
-
?
(S)-N-benzyl-1-phenylethylamine + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
1,2,3,4-tetrahydro-2-naphthylamine + O2 + H2O
? + NH3 + H2O2
show the reaction diagram
-
23% of the activity compared to cyclohexylamine
-
?
1,2-cyclohexanediamine + O2 + H2O
cyclohexaneamine + NH3 + H2O2
show the reaction diagram
-
18% of the activity compared to cyclohexylamine
-
?
1-(4-chlorophenyl)ethanamine + O2 + H2O
?
show the reaction diagram
-
35% activity compared to cyclohexylamine
-
-
?
1-(4-fluorophenyl)ethanamine + O2 + H2O
1-(4-fluorophenyl)ethanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
1-(4-fluorophenyl)ethanamine + O2 + H2O
?
show the reaction diagram
-
61% activity compared to cyclohexylamine
-
-
?
1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline + + O2 + H2O
?
show the reaction diagram
1-(4-methylphenyl)ethanamine + O2 + H2O
?
show the reaction diagram
-
5% activity compared to cyclohexylamine
-
-
?
1-(4-methylphenyl)methanamine + O2 + H2O
?
show the reaction diagram
-
1% activity compared to cyclohexylamine
-
-
?
1-(naphthalen-1-yl)ethanamine + O2 + H2O
?
show the reaction diagram
-
1% activity compared to cyclohexylamine
-
-
?
1-indanamine + O2 + H2O
1-indanone + NH3 + H2O2
show the reaction diagram
-
27% activity compared to cyclohexylamine
-
-
?
1-phenylethanamine + O2 + H2O
1-phenylacetaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
1-phenylethanamine + O2 + H2O
1-phenylethanone + NH3 + H2O2
show the reaction diagram
-
48% activity compared to cyclohexylamine
-
-
?
2-amino-4-phenylbutane + O2 + H2O
4-phenylbutan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
2-amino-5-methylhexane + O2 + H2O
5-methylhexane-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
2-aminocyclohexanol + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
2-aminoheptane + O2 + H2O
heptan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
2-aminonorbornane + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
2-aminopentane + O2 + H2O
pentan-2-one + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
2-ethyl-1-hexylamine + O2 + H2O
2-ethylhexanaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
2-heptylamine + O2 + H2O
heptan-2-one + NH3 + H2O2
show the reaction diagram
-
24% activity compared to cyclohexylamine
-
-
?
2-methyl-1,2,3,4-tetrahydroquinoline + O2 + H2O
(R)-2-methyl-1,2,3,4-tetrahydroquinoline + NH3 + H2O2
show the reaction diagram
2-methylcyclohexanamine + O2 + H2O
2-methylcyclohexanone + NH3 + H2O2
show the reaction diagram
2-methylcyclohexanamine + O2 + H2O
?
show the reaction diagram
-
56% activity compared to cyclohexylamine
-
-
?
2-methylpropan-1-amine + O2 + H2O
?
show the reaction diagram
-
0.1% activity compared to cyclohexylamine
-
-
?
3-phenylpropan-1-amine + H2O + O2
? + NH3 + H2O2
show the reaction diagram
4-methylbenzylamine + O2 + H2O
4-methylbenzaldehyde + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
4-methylcyclohexanamine + O2 + H2O
4-methylcyclohexanone + NH3 + H2O2
show the reaction diagram
-
41% of the activity with cyclohexylamine
-
-
?
4-methylcyclohexylamine + O2 + H2O
?
show the reaction diagram
-
133% activity compared to cyclohexylamine
-
-
?
4-methylpiperidine + O2 + H2O
?
show the reaction diagram
-
0.1% activity compared to cyclohexylamine
-
-
?
4-phenylbutan-2-amine + O2 + H2O
?
show the reaction diagram
-
12% activity compared to cyclohexylamine
-
-
?
5-methylhexan-2-amine + O2 + H2O
?
show the reaction diagram
-
9% activity compared to cyclohexylamine
-
-
?
6-amino-2-methylheptan-2-ol + O2 + H2O
?
show the reaction diagram
-
0.1% activity compared to cyclohexylamine
-
-
?
benzylamine + O2 + H2O
benzaldehyde + NH3 + H2O2
show the reaction diagram
bicyclo[2.2.1]heptan-2-amine + O2 + H2O
?
show the reaction diagram
-
2% activity compared to cyclohexylamine
-
-
?
butan-2-amine + O2 + H2O
?
show the reaction diagram
-
3% activity compared to cyclohexylamine
-
-
?
cycloheptanamine + O2 + H2O
?
show the reaction diagram
-
75% activity compared to cyclohexylamine
-
-
?
cycloheptylamine + O2 + H2O
cycloheptanone + NH3 + H2O2
show the reaction diagram
cyclohexylamine + O2 + H2O
cyclohexanone + NH3 + H2O2
show the reaction diagram
cyclooctanamine + O2 + H2O
?
show the reaction diagram
-
23% activity compared to cyclohexylamine
-
-
?
cyclooctanamine + O2 + H2O
cyclooctanone + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
cyclopentylamine + O2 + H2O
cyclopentanone + NH3 + H2O2
show the reaction diagram
hexan-1-amine + O2 + H2O
?
show the reaction diagram
-
1% activity compared to cyclohexylamine
-
-
?
L-valine ethyl ester
D-valine ethyl ester
show the reaction diagram
N-methylcyclohexanamine + O2 + H2O
?
show the reaction diagram
N-methylcyclohexylamine + O2 + H2O
cyclohexanone + methylamine + H2O2
show the reaction diagram
racemic phenylalanine ethyl ester
L-phenylalanine ethyl ester
show the reaction diagram
racemic valine ethyl ester
D-valine ethyl ester
show the reaction diagram
secondary butylamine + O2 + H2O
butanone + NH3 + H2O2
show the reaction diagram
trans-2-aminocyclohexanol + O2 + H2O
?
show the reaction diagram
-
16% activity compared to cyclohexylamine
-
-
?
additional information
?
-