1.4.1.B2: L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)
This is an abbreviated version!
For detailed information about L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+), go to the full flat file.
Reaction
Synonyms
3,5-DAHDH, Kdd
ECTree
1.4.1.B2 L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.4.1.B2 - L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
L-erythro-3,5-diaminohexanoate + H2O + acetylpyridine-NAD+
5-amino-3-oxohexanoate + NH3 + acetylpyridine-NADH + H+
-
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + deamino-NAD+
5-amino-3-oxohexanoate + NH3 + deamino-NADH + H+
-
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
additional information
?
-
-
the enzyme barely shows any activity towards (S)-beta-aminobutyric acid, beta-alanine, (R)-beta-homoserine, (R)-beta-homomethionine, (S)-beta-homoglutamine, (R)-beta-phenylalanine, and (S)-beta-homolysine
-
-
?
(R)-beta-homomethionine + H2O + NADP+
? + NH3 + NADPH + H+
-
-
-
?
(R)-beta-homomethionine + H2O + NADP+
? + NH3 + NADPH + H+
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NAD+
5-amino-3-oxohexanoate + NH3 + NADH + H+
-
either NAD+ or NADP+ serve as coenzyme. Double-reciprocal plots of activity versus pyridine nucleotide concentration are biphasic. The Km values for NADP+ are lower but a higher Vmax is observed with NAD+
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NAD+
5-amino-3-oxohexanoate + NH3 + NADH + H+
-
Vmax/Km for NADP+ is 10-16fold higher, depending on KM-value
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NAD+
5-amino-3-oxohexanoate + NH3 + NADH + H+
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
(S)-5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
either NAD+ or NADP+ serve as coenzyme. Double-reciprocal plots of activity versus pyridine nucleotide concentration are biphasic. The Km values for NADP+ are lower but a higher Vmax is observed with NAD+
-
-
?
L-erythro-3,5-diaminohexanoate + H2O + NADP+
5-amino-3-oxohexanoate + NH3 + NADPH + H+
-
Vmax/Km for NADP+ is 10-16fold higher, depending on KM-value
-
-
?
