1.4.1.3: glutamate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glutamate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

At5g07440, At5g18170, dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)), dual-coenzyme specific glutamate dehydrogenase, GDH, gdh-1, GDH1, GDH2, GDH3, GdhA, gdhA_1, GDHB, GDHII, GLDH, GLUD1, GLUD2, GluDH, glutamate dehydrogenase, glutamate dehydrogenase 1, glutamate dehydrogenase 2, glutamic acid dehydrogenase, glutamic dehydrogenase, hGDH1, hGDH2, hGLUD1, hGLUD2, housekeeping glutamate dehydrogenase, L-glutamate dehydrogenase, L-glutamic acid dehydrogenase, Legdh1, Membrane protein 50, MP50, NAD(P)+-dependent glutamate dehydrogenase, NAD(P)-dependent GDH, NAD(P)-dependent glutamate dehydrogenase, NAD(P)-glutamate dehydrogenase, NAD(P)H-dependent glutamate dehydrogenase, NAD(P)H-utilizing glutamate dehydrogenase, NADH-GDH, NADH-glutamate dehydrogenase, TTC1211, TTC1212, TtGDH

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.3 glutamate dehydrogenase [NAD(P)+]

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Results	in table
91	Activating Compound
1957	AA Sequence
6	Application
1	CAS Registry Number
38	Cloned(Commentary)
184	Cofactor
23	Crystallization (Commentary)
54	Disease/ Diagnostics
1	Expression
36	General Information
13	General Stability
71	IC50 Value
153	Inhibitors
63	Ki Value [mM]
445	KM Value [mM]
42	Localization
7	Metals/Ions
76	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
185	Organism
11	Pathway
187	PDB ID
73	pH Optimum
12	pH Range
4	pH Stability
2	pI Value
3	Posttranslational Modification
92	Protein Variants
60	Purification (Commentary)
7	Reaction
4	Reaction Type
148	Reference
3	Renatured (Commentary)
139	Source Tissue
67	Specific Activity [micromol/min/mg]
14	Storage Stability
206	Substrates and Products (Substrate)
60	Subunits
118	Synonyms
1	Systematic Name
21	Temperature Optimum [°C]
10	Temperature Range [°C]
49	Temperature Stability [°C]
127	Turnover Number [1/s]

pH Range

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pH Range on EC 1.4.1.3 - glutamate dehydrogenase [NAD(P)+]

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6.5 - 8

Thermococcus litoralis

Q56304

pH 6.5: about 50% of maximal activity, pH 8.0: about 70% of maximal activity

7 - 8

7 - 9

pH 7.0: about 50% of maximal activity, pH 9.0: about 35% of maximal activity

7.4 - 8.5

7.5 - 8

half activity of glutamate deamination compared to pH 9.5

391634

7.5 - 8.8

Glycine max

NAD(P)H + 2-oxoglutarate + NH3, more than 50% of activity maximum at pH 7.5 and 8.8

391608

7.75 - 8

Homo sapiens

maximal specific activity in TRA buffer

700428

7.9 - 9

uncultured bacterium

activity range, profile overview

724653

8 - 9.2

Glycine max

deamination, more than 50% of activity maximum at pH 8.0 and 9.2

391608