Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.1.18: lysine 6-dehydrogenase

This is an abbreviated version!
For detailed information about lysine 6-dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.18

Reaction

L-lysine
+
NAD+
 +
H2O
=
(S)-2-amino-6-oxohexanoate
 +
NADH
 +
H+
 +
NH3

Synonyms

L-lysine 6-dehydrogenase, L-lysine 6-dehydrogenase (deaminating), L-lysine epsilon-dehydrogenase, Lys 6-DH, LysDH, lysine 6-dehydrogenase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.18 lysine 6-dehydrogenase

Inhibitors

Inhibitors on EC 1.4.1.18 - lysine 6-dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6-amino-n-caproate
inhibition 20% by 10 mM 6-amino-n-caproate
DTNB
-
almost complete inhibition in presence of NAD+, 40% inhibition in presence of L-lysine
HgCl2
L-leucine
inhibition 50% by 10 mM L-leucine
L-norleucine
inhibition 20% by 10 mM L-norleucine
L-ornithine
inhibition 10% by 10 mM L-ornithine
N-ethylmaleimide
p-chloromercuribenzoate
Pb(acetate)2
1 mM, 37% inhibition