1.4.1.16: diaminopimelate dehydrogenase

This is an abbreviated version!
For detailed information about diaminopimelate dehydrogenase, go to the full flat file.

Reaction

Synonyms

BAB07799, BF3690, DAPDH, DDH, meso-2,6-diaminopimelate dehydrogenase, meso-alpha,epsilon-diaminopimelate dehydrogenase, meso-DAPDH, meso-diaminopimelate dehydrogenase, NADP+-dependent meso-diaminopimelate dehydrogenase, Sth1425, Theth_1310

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.1 With NAD⁺ or NADP⁺ as acceptor

                1.4.1.16 diaminopimelate dehydrogenase

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Results	in table
3529	AA Sequence
4	Application
1	CAS Registry Number
20	Cloned(Commentary)
84	Cofactor
8	Crystallization (Commentary)
4	General Information
5	IC50 Value
77	Inhibitors
77	kcat/KM [mM/s]
10	Ki Value [mM]
133	KM Value [mM]
1	Metals/Ions
15	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
120	Organism
6	Pathway
38	PDB ID
21	pH Optimum
3	pH Range
4	pH Stability
52	Protein Variants
18	Purification (Commentary)
5	Reaction
3	Reaction Type
111	Reference
34	Specific Activity [micromol/min/mg]
5	Storage Stability
211	Substrates and Products (Substrate)
17	Subunits
42	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
12	Temperature Stability [°C]
102	Turnover Number [1/s]

KI Value

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KI Value on EC 1.4.1.16 - diaminopimelate dehydrogenase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0042 - 0.023

(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid

4 entries

2

D-2,6-diaminopimelate

Corynebacterium glutamicum

-

-

391505

4

D-alpha,epsilon-diaminopimelate

Lysinibacillus sphaericus

-

-

391513

8.5

L-2,6-diaminopimelate

Corynebacterium glutamicum

-

-

391505

0.005

L-2-amino-6-methylene-pimelate

Lysinibacillus sphaericus

-

-

391524

3.12

L-alpha,epsilon-diaminopimelate

Lysinibacillus sphaericus

-

-

391513

4.16

meso-alpha,delta-Diaminoadipate

Lysinibacillus sphaericus

-

-

391513

0.0042

(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Corynebacterium glutamicum

P04964

reductive amination

391523

0.0042

(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Lysinibacillus sphaericus

-

competitive inhibition of L-2-amino-6-oxoheptanedioate

2149

0.023

(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Corynebacterium glutamicum

P04964

oxidative deamination at pH 7.8

391523

0.023

(2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid

Lysinibacillus sphaericus

-

noncompetitive inhibition of meso-diaminopimelate

2149