1.4.1.15: lysine dehydrogenase

This is an abbreviated version!
For detailed information about lysine dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.15

1.4.1.15

saccharopine

pipecolate

pomeroyi

6-dehydrogenase

silicibacter

analysis

Reaction

Synonyms

L-lysine epsilon dehydrogenase, LysDH

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.15 lysine dehydrogenase

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Results	in table
22	Activating Compound
1	Application
1	CAS Registry Number
5	Cofactor
1	Expression
2	General Information
1	Inhibitors
3	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
126	Organism
3	pH Optimum
1	Purification (Commentary)
2	Reaction
4	Reaction Type
120	Reference
1	Source Tissue
20	Specific Activity [micromol/min/mg]
38	Substrates and Products (Substrate)
1	Subunits
2	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.4.1.15 - lysine dehydrogenase

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4-hydroxylysine + NADP+

alpha-amino-gamma-hydroxyadipate-semialdehyde + NADPH

2 entries

5-hydroxylysine + NADP+

alpha-amino-delta-hydroxyadipate-semialdehyde + NADPH

2 entries

L-glutamate + 3-acetylpyridine-NAD+

L-glutamine + 2-oxoglutarate + 3-acetylpyridine-NADH + H+

Agrobacterium tumefaciens

391499

L-glutamate + deamino-NAD+

L-glutamine + 2-oxoglutarate + deamino-NADH + H+

Agrobacterium tumefaciens

391499

L-lysine + NAD+

1,2-didehydropiperidine-2-carboxylate + NH3 + NADH

Homo sapiens

391496

L-lysine + NAD+

1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+

Ruegeria pomeroyi

725167

L-lysine + NAD+ + H2O

1,2-didehydropiperidine-6-carboxylate + NH3 + NADH

27 entries

S-(2-aminoethyl)-L-cysteine + NADP+ + H2O

S-(2-oxoethyl)-L-cysteine + NADPH + NH3

2 entries

additional information

Ruegeria pomeroyi

LysDH directly converts L-lysine to alpha-aminoadipic-delta-semialdehyde

725167