1.4.1.1: alanine dehydrogenase
This is an abbreviated version!
For detailed information about alanine dehydrogenase, go to the full flat file.
Word Map on EC 1.4.1.1
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1.4.1.1
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burn
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children
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postburn
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sham
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full-thickness
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flame
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admitted
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superficial
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admission
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resuscitation
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injured
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trauma
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sepsis
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inflict
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burn-induced
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ringer
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sacrificed
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third-degree
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anesthetized
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immersion
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xanthomonas
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barley
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child
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demographic
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dress
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partial-thickness
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victim
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sugarcane
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accident
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home
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second-degree
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xylella
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dorsum
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work-related
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postinjury
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thermostat
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epithelialization
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debridement
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hereinafter
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1-methylcyclopropene
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biotechnology
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synthesis
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fastidiosa
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heater
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toddler
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hypermetabolic
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delicious
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guadeloupe
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kitchen
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diphenylamine
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medicine
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eschar
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nutrition
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analysis
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shower
- 1.4.1.1
-
burn
- children
-
postburn
-
sham
-
full-thickness
-
flame
-
admitted
-
superficial
-
admission
-
resuscitation
-
injured
-
trauma
-
sepsis
-
inflict
-
burn-induced
-
ringer
-
sacrificed
-
third-degree
-
anesthetized
-
immersion
-
xanthomonas
- barley
- child
-
demographic
-
dress
-
partial-thickness
-
victim
-
sugarcane
-
accident
-
home
-
second-degree
-
xylella
-
dorsum
-
work-related
-
postinjury
-
thermostat
-
epithelialization
-
debridement
-
hereinafter
- 1-methylcyclopropene
- biotechnology
- synthesis
-
fastidiosa
-
heater
-
toddler
-
hypermetabolic
-
delicious
-
guadeloupe
-
kitchen
- diphenylamine
- medicine
-
eschar
- nutrition
- analysis
-
shower
Reaction
Synonyms
(S)alanine dehydrogenase, (S)alanine:NAD oxidoreductase, 40 kDa antigen, ADH, AF1665, ALADH, alanine dehydrogenase, alanine oxidative deaminase, alanine oxidoreductase, ALD, AldA, alpha-alanine dehydrogenase, ApalaDH, AsAlaDH, CQA66_00465, dehydrogenase, alanine, glyoxylate reductive aminase, GxrA, HAADH1, HAADH2, L-Ala dehydrogenase, L-AlaDH, L-AlaDH-Bs, L-alanine dehydrogenase, MtbALD, NAD(H)-dependent L-alanine dehydrogenase, NAD+ dependent amino acid dehydrogenase, NAD+-dependent alanine dehydrogenase, NAD-dependent alanine dehydrogenase, NAD-linked alanine dehydrogenase, NADH-dependent alanine dehydrogenase, OF4Ald, PlaAlaDH, PvRA, pyruvate reductive aminase, Rv2780, ScALD, SCO1773, SheAlaDH, TB43
ECTree
1.4.1.1 alanine dehydrogenaseAdvanced search results
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results (Application
Application on EC 1.4.1.1 - alanine dehydrogenase
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APPLICATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
analysis
biotechnology
heterologous expression of the Bacillus subtilis AlaDH in Lactococcus lactis using the promoter of lactate dehydrogenase from Streptococcus thermophilus leads to a better alanine production in the recombinant strain
medicine
nutrition
synthesis
additional information
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alanine dehydrogenase activity is necessary for an adequate cellular response to nitrogen starvation, is required for efficient degradation of phycobilisomes only during nitrogen starvation
analysis
alanine dehydrogenase from Streptomyces anulatus can be used as a bioreceptor in an ammonium biosensor that can detect ammonium ions in water samples. The sensor shows linear response in the range of 0.1-300mM NH4+ with the detection limit of 0.01 mM NH4+ and response time of 20 s. The sensor is showing good response at wide pH range (pH 5-11) and temperature range (20-50°C) suggesting its usage at ambient and non-ambient conditions. The sensor is successfully validated with Nessler's reagent method by using different water samples
analysis
an enzymatic assay system to eliminate or measure D-Ala, which is reported to affect the taste of seafoods or sake, is constructed using alanine racemase (L-AlaR from Synechocystis sp. PCC6803) and L-alanine dehydrogenase (L-AlaDH from Phormidium lapideum). Using the assay system, the D-Ala contents of 7 crustaceans, i. e. mosa shrimp (Argis lar, Mosaebi), spiny lebbeid (Lebbeus groenlandicus, Oniebi), deepwater prawn (Pandalus eous,Amaebi), flathead lobster (Ibacus ciliates, Uchiwaebi), snow crab (Chionoecetes opilio, Zuwaigani), red snow crab (Chionoecetes japonicus, Benizuwaigani), and horsehair crab (Erimacrus isenbeckii, Kegani), are determined
analysis
Streptomyces anulatus MTCC 2528
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alanine dehydrogenase from Streptomyces anulatus can be used as a bioreceptor in an ammonium biosensor that can detect ammonium ions in water samples. The sensor shows linear response in the range of 0.1-300mM NH4+ with the detection limit of 0.01 mM NH4+ and response time of 20 s. The sensor is showing good response at wide pH range (pH 5-11) and temperature range (20-50°C) suggesting its usage at ambient and non-ambient conditions. The sensor is successfully validated with Nessler's reagent method by using different water samples
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medicine
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L-alanine catabolism can be conferred on Mycobacterium bovis BCG by introduction of the gene encoding Ald of Mycobacterium tuberculosis, restoration of Ald activity does not change the in vivo growth of BCG in macrophages or mice, and protection against aerosol Mycobacterium tuberculosis infection is not altered by addition of the gene encoding Ald to the BCG vaccine
medicine
an Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
medicine
plausible application of Ald inhibitors for treatment of tuberculosis. An Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
medicine
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an Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
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medicine
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plausible application of Ald inhibitors for treatment of tuberculosis. An Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
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medicine
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plausible application of Ald inhibitors for treatment of tuberculosis. An Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
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medicine
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an Ald-specific inhibitor and respiration inhibitory antitubercular drugs, such as Q203 and BDQ, are likely to enable more efficient therapies for tuberculosis
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nutrition
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Lactococcus lactis strain NZ9000 expressing the enzyme from Bacillus subtilis can be used in imporvement of dairy fermentation for developing healthy yogurts with sweet taste or other fermented dairy foods
nutrition
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Lactococcus lactis strain NZ9000 expressing the enzyme from Bacillus subtilis can be used in imporvement of dairy fermentation for developing healthy yogurts with sweet taste or other fermented dairy foods
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synthesis
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batch synthesis of L-Ala at room temperature via reductive amination of pyruvate
synthesis
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continuous production of 3-fluoro-L-alanine with alanine dehydrogenase
synthesis
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alterating of cofactor specificity from NADH to NADPH via protein engineering for application as a regenerating enzyme in coupled reactions with NADPH-dependent alcohol dehydrogenases. Mutant D196A/L197R can be applied in a coupled oxidation/transamination reaction of the dicyclic dialcohol isosorbide to its diamines, catalyzed by Ralstonia sp. alcohol dehydrogenase and Paracoccus denitrificans omega-aminotransferase, allowing recycling of NADP+ and L-Ala. Recycling factors of 33 for NADP+ and 13 for L-Ala are observed
synthesis
the enzyme can be used as heterogeneous biocatalyst for reductive aminations of 2-oxoacids
synthesis
the enzyme from Amycolatopsis sulphurea has the ability to produce valuable molecules for various industrial purposes and represents a potential biocatalyst for biotechnological applications
synthesis
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the enzyme can be used as heterogeneous biocatalyst for reductive aminations of 2-oxoacids
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