1.3.8.4: isovaleryl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about isovaleryl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.4

1.3.8.4

acidemia

acyl-coa

inborn

3-methylcrotonyl-coa

isovalerylglycine

medium-chain

lethargy

flavoenzyme

isobutyryl-coa

acylcarnitine

isovalerylcarnitine

flavoprotein:ubiquinone

glutaryl-coa

2-methylbutyryl-coa

3-hydroxyisovaleric

octanoyl-coa

sweaty

diagnostics

medicine

Reaction

Synonyms

acyl-CoA dehydrogenase, EC 1.3.99.10, i3VD, iso(3)valeryl-CoA dehydrogenase, isovaleric-CoA dehydrogenase, isovaleroyl-coenzyme A dehydrogenase, isovaleryl-coenzyme A dehydrogenase, IVD, IVDH, LiuA, Pden_3633, SBCAD, short/branched chain acyl-CoA dehydrogenase

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.8 With a flavin as acceptor

1.3.8.4 isovaleryl-CoA dehydrogenase

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Results	in table
4	Activating Compound
4063	AA Sequence
3	Application
1	CAS Registry Number
21	Cloned(Commentary)
21	Cofactor
1	Crystallization (Commentary)
88	Disease/ Diagnostics
2	Expression
27	General Information
33	Inhibitors
6	kcat/KM [mM/s]
6	Ki Value [mM]
59	KM Value [mM]
25	Localization
18	Molecular Weight [Da]
57	Natural Substrates/ Products (Substrates)
53	Organism
5	Pathway
10	pH Optimum
49	Protein Variants
15	Purification (Commentary)
1	Reaction
3	Reaction Type
52	Reference
1	Renatured (Commentary)
31	Source Tissue
75	Specific Activity [micromol/min/mg]
1	Storage Stability
136	Substrates and Products (Substrate)
8	Subunits
34	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
7	Temperature Stability [°C]
17	Turnover Number [1/s]

KM Value

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KM Value on EC 1.3.8.4 - isovaleryl-CoA dehydrogenase

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0.0019 - 0.0035

(S)-2-methylbutyryl-CoA

2 entries

0.025 - 0.0362

butyryl-CoA

2 entries

0.002

electron transfer protein

Homo sapiens

P26440

pH 8.0, 30°C, calculated per monomer

742009

0.0038

electron-transfer flavoprotein

Homo sapiens

391201

0.00043

FAD

Rattus norvegicus

391203

0.02 - 0.0338

hexanoyl-CoA

2 entries

0.5 - 0.79

isobutyryl-CoA

2 entries

0.001 - 0.9

isovaleryl-CoA

36 entries

0.0167 - 0.4

n-valeryl-CoA

4 entries

0.51 - 0.833

phenazine methosulfate

2 entries

0.0105 - 0.0167

valeryl-CoA

2 entries

additional information

Homo sapiens

kinetics

655248