Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.3.8.1: short-chain acyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about short-chain acyl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.3.8.1

Reaction

a short-chain acyl-CoA
+
electron-transfer flavoprotein
=
a short-chain trans-2,3-dehydroacyl-CoA
 +
reduced electron-transfer flavoprotein

Synonyms

3-hydroxyacyl CoA reductase, ACADS, Acfer_0556, Acfer_1477, acyl-CoA dehydrogenase short chain, BCAD, BCD, bcd2, BcdAf, bSCAD, butyryl CoA dehydrogenase, butyryl coenzyme A dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, butyryl-CoA dehydrogenase/Etf complex, CD1054, dehydrogenase, butyryl coenzyme A, EC 1.3.2.1, EC 1.3.99.2, enoyl-coenzyme A reductase, ethylene reductase, HADHSC, non-dissociating bifurcating Etf-Bcd complex, SCAD, ScdA, short chain acyl-CoA dehydrogenase, short-chain 3-hydroxyacyl-CoA dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, short-chain acylCoA dehydrogenase, unsaturated acyl coenzyme A reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.1 short-chain acyl-CoA dehydrogenase

Substrates Products

Substrates Products on EC 1.3.8.1 - short-chain acyl-CoA dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(3,3-difluorobutyryl)pantetheine + phenazine methosulfate + dichlorophenolindophenol
3-fluoro-2-butenoylpantetheine + HF
show the reaction diagram
-
-
-
?
(E)-2-butenoyl-CoA + reduced methylviologen
? + oxidized methylviologen
show the reaction diagram
-
-
-
-
?
(S)-2-methylbutyryl-CoA + phenazine methosulfate + dichloroindophenol
(S)-2-methyl-2-butenoyl-CoA + reduced acceptor
show the reaction diagram
-
6.0% of activity with butyryl-CoA
-
?
2-azabutyryl-CoA + ?
?
show the reaction diagram
-
substrate may be converted by intrinsic hydratase activity of the enzyme to 2-azaacetyl-CoA
-
-
?
2-butenoyl-CoA + reduced acceptor
butanoyl-CoA + acceptor
show the reaction diagram
-
reduction in vivo
-
-
r
2-butenoyl-CoA + reduced acceptor
butyryl-CoA + acceptor
show the reaction diagram
-
trans-addition of hydrogen
-
?
2-butenoyl-CoA + reduced electron transfer flavoprotein
butanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-hexenoyl-CoA + reduced electron transfer flavoprotein
hexanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-methylbutanoyl-CoA + acceptor
2-methyl-2-butenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
r
2-methylbutyryl-CoA + electron acceptor
2-methyl-2-butenoyl-CoA + reduced acceptor
show the reaction diagram
-
highest activity
-
-
?
2-methylpropionyl-CoA + phenazine methosulfate + dichloroindophenol
2-methylpropenoyl-CoA + reduced acceptor
show the reaction diagram
-
1.5% of activity with butyryl-CoA
-
?
2-pentenoyl-CoA + reduced electron transfer flavoprotein
pentanoyl-CoA + electron transfer protein
show the reaction diagram
-
enzyme functions as C3-C6 enoyl-CoA reductase in vivo and catalyzes the oxidation of butyryl-CoA and related substrates in vitro
-
r
2-propenoyl-CoA + reduced electron transfer flavoprotein
propanoyl-CoA + electron transfer protein
show the reaction diagram
3-fluoropropionyl-CoA + phenazine methosulfate + dichlorophenolindophenol
2-propenoyl-CoA + HF
show the reaction diagram
-
-
-
?
3-hydroxybutyryl-CoA + acceptor
acetoacetyl-CoA + reduced acceptor
show the reaction diagram
4-methylpentanoyl-CoA + phenazine methosulfate + dichloroindophenol
4-methyl-2-pentenoyl-CoA + reduced acceptor
show the reaction diagram
-
18.0% of activity with butyryl-CoA
-
?
acrolein + reduced methylviologen
? + oxidized methylviologen
show the reaction diagram
-
-
-
-
?
acryloyl-CoA + benzyl viologen
propanoyl-CoA + reduced benzyl viologen
show the reaction diagram
acryloyl-CoA + reduced methylviologen
propanoyl-CoA + oxidized methylviologen
show the reaction diagram
-
-
-
-
?
butanoyl-CoA + acceptor
2-butenoyl-CoA + reduced acceptor
show the reaction diagram
butanoyl-CoA + acceptor
but-2-enoyl-CoA + reduced acceptor
show the reaction diagram
butanoyl-CoA + FAD
2-butenoyl-CoA + FADH2
show the reaction diagram
butanoyl-CoA + FAD
but-2-enoyl-CoA + FADH2
show the reaction diagram
-
-
-
?
butanoyl-CoA + FAD
trans-2,3-dehydrobutanoyl-CoA + FADH2
show the reaction diagram
-
-
-
-
?
butanoyl-CoA + oxidized acceptor
crotonyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
r
butyryl-CoA + 2,6-dichloro-phenolindophenol
but-2-enoyl-CoA + reduced 2,6-dichloro-phenolindophenol
show the reaction diagram
-
-
-
-
r
butyryl-CoA + 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
2-butenoyl-CoA + reduced acceptor
show the reaction diagram
butyryl-CoA + electron acceptor
2-butenoyl-CoA + reduced acceptor
show the reaction diagram
butyryl-CoA + electron transfer flavoprotein
2-butenoyl-CoA + reduced electron transfer flavoprotein
show the reaction diagram
-
-
-
-
?
butyryl-CoA + electron transfer flavoprotein
crotonyl-CoA + reduced electron transfer flavoprotein
show the reaction diagram
-
-
-
-
?
butyryl-CoA + electron-transferring flavoprotein
2-butenoyl-CoA + reduced electron-transferring flavoprotein
show the reaction diagram
-
-
-
-
?
butyryl-CoA + ferricenium
2-butenoyl-CoA + ferrocene
show the reaction diagram
-
-
-
-
?
butyryl-CoA + ferricytochrome c
butenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
r
butyryl-CoA + ferrocenium
2-butenoyl-CoA + ferrocene
show the reaction diagram
-
-
-
-
?
butyryl-CoA + O2
2-butenoyl-CoA + H2O2
show the reaction diagram
butyryl-CoA + oxidized acceptor
crotonyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
?
butyryl-CoA + pyocyanine + triphenyltetrazolium chloride
2-butenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
r
crotonyl-CoA + 2 NADH + 2 Fd-
butyryl-CoA + 2 NAD+ + 2 Fd2-
show the reaction diagram
crotonyl-CoA + electron acceptor
butyryl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
?
crotonyl-CoA + electron transfer flavoprotein
butyryl-CoA + ?
show the reaction diagram
-
-
-
?
crotonyl-CoA + O2 + 2 NADH + 2 H+
butanoyl-CoA + H2O2 + 2 NAD+
show the reaction diagram
crotonyl-CoA + reduced acceptor
butyryl-CoA + oxidized acceptor
show the reaction diagram
-
-
-
-
?
crotonyl-CoA + reduced ferredoxin
butanoyl-CoA + oxidized ferredoxin
show the reaction diagram
cyclobutanecarboxyl-CoA + phenazine ethosulfate + dichloroindophenol
cyclo-2-butenecarboxyl-CoA + reduced acceptor
show the reaction diagram
cycloheptanecarboxyl-CoA + phenazine ethosulfate + dichloroindophenol
cyclo-2-heptenecarboxyl-CoA + reduced acceptor
show the reaction diagram
-
3.2% of activity with butyryl-CoA
-
?
cyclohexanecarboxyl-CoA + phenazine ethosulfate + dichloroindophenol
cyclo-2-hexenecarboxyl-CoA + reduced acceptor
show the reaction diagram
-
6.7% of activity with butyryl-CoA
-
?
cyclopentanecarboxyl-CoA + phenazine ethosulfate + dichloroindophenol
cyclo-2-pentenecarboxyl-CoA + reduced acceptor
show the reaction diagram
ethyl vinyl ketone + reduced methylviologen
? + oxidized methylviologen
show the reaction diagram
-
-
-
-
?
heptanoyl-CoA + electron acceptor
2-heptenoyl-CoA + reduced acceptor
show the reaction diagram
hexanoyl-CoA + acceptor
2-hexenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
r
hexanoyl-CoA + acceptor
hex-2-enoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
hexanoyl-CoA + electron acceptor
2-hexenoyl-CoA + reduced acceptor
show the reaction diagram
hexanoyl-CoA + electron transfer flavoprotein
2-hexenoyl-CoA + reduced acceptor
show the reaction diagram
hexanoyl-CoA + FAD
hex-2-enoyl-CoA + FADH2
show the reaction diagram
-
-
-
?
hexanoyl-CoA + phenazine methosulfate + dichloroindophenol
2-hexenoyl-CoA + reduced acceptor
show the reaction diagram
N-acetyl-S-acryloyl-cysteamine + reduced methylviologen
? + oxidized methylviologen
show the reaction diagram
-
-
-
-
?
octanoyl-CoA + electron acceptor
2-octenoyl-CoA + reduced acceptor
show the reaction diagram
octanoyl-CoA + electron transfer flavoprotein
octenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
?
octanoyl-CoA + electron transfer protein
2-octenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
octanoyl-CoA + Meldola's Blue + iodonitrotetrazolium chloride
2-octenoyl-CoA + reduced acceptor
show the reaction diagram
pentanoyl-CoA + 2,6-dichlorophenolindophenol + phenazine ethosulfate
2-pentenoyl-CoA + reduced acceptor
show the reaction diagram
pentanoyl-CoA + acceptor
pent-2-enoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
pentanoyl-CoA + electron transfer flavoprotein
2-pentenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
pentanoyl-CoA + FAD
pent-2-enoyl-CoA + FADH2
show the reaction diagram
-
-
-
?
pentanoyl-CoA + phenazine methosulfate
2-pentenoyl-CoA + reduced acceptor
show the reaction diagram
pentenoyl-CoA + oxidized electron transfer flavoprotein
valeryl-CoA + reduced electron transfer flavoprotein
show the reaction diagram
-
-
-
-
?
propionyl-CoA + 2,6-dichlorophenolindophenol
2-propenoyl-CoA + reduced acceptor
show the reaction diagram
propionyl-CoA + electron transfer flavoprotein
2-propenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
propionyl-CoA + phenazine methosulfate
2-propenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
?
reduced ferredoxin + NAD+ + H+
oxidized ferredoxin + NADH
show the reaction diagram
S-butyrylpantetheine + phenazine ethosulfate + dichloroindophenol
S-but-2-eneoylpantetheine + reduced acceptor
show the reaction diagram
-
51.0% of activity with butyryl-CoA
-
?
valeryl-CoA + electron acceptor
2-pentenoyl-CoA + reduced acceptor
show the reaction diagram
-
-
-
-
?
additional information
?
-