1.3.5.3: protoporphyrinogen IX dehydrogenase (quinone)
This is an abbreviated version!
For detailed information about protoporphyrinogen IX dehydrogenase (quinone), go to the full flat file.
Reaction
Synonyms
HemG, HemG protein, PPO, PPOX, PPX, PPX1, protogen oxidase, protoporphyrinogen IX dehydrogenase (menaquinone), protoporphyrinogen IX oxidase
ECTree
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Substrates Products
Substrates Products on EC 1.3.5.3 - protoporphyrinogen IX dehydrogenase (quinone)
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REACTION DIAGRAM
protoporphyrinogen IX + 3 plastoquinone
protoporphyrin IX + 3 plastoquinol
-
-
-
-
?
protoporphyrinogen IX + 3 triphenyltetrazolium chloride
protoporphyrin IX + ?
-
artificial electron acceptor
-
-
?
additional information
?
-
-
potential electron acceptors, i.e. 2, 6-dichloroindophenol, phenazine methosulfate, menadione, and vitamin K1, respectively, directly oxidize the substrate in the absence of HemG
-
-
?
protoporphyrin IX + 3 menadiol
-
the enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments
-
-
?
protoporphyrinogen IX + 3 menadione
protoporphyrin IX + 3 menadiol
-
HemG is specific for protoporphyrinogen. Neither mesoporphyrinogen nor coproporphyrinogen is oxidized by HemG
-
-
?
protoporphyrin IX + 3 menaquinol
-
-
-
-
?
protoporphyrinogen IX + 3 menaquinone
protoporphyrin IX + 3 menaquinol
-
under anaerobic conditions
-
-
?
protoporphyrin IX + 3 ubiquinol
-
-
-
-
?
protoporphyrinogen IX + 3 ubiquinone
protoporphyrin IX + 3 ubiquinol
-
under aerobic conditions
-
-
?