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1.3.2.3: L-galactonolactone dehydrogenase

This is an abbreviated version!
For detailed information about L-galactonolactone dehydrogenase, go to the full flat file.

Word Map on EC 1.3.2.3

Reaction

L-galactono-1,4-lactone
+
2 ferricytochrome c
=
L-ascorbate
+ 2 ferrocytochrome c + 2 H+

Synonyms

dehydrogenase, galactonolactone, ferricytochrome c oxidoreductase, galactono-1,4-lactone dehydrogenase, galactonolactone dehydrogenase, GALDH, GalL dehydrogenase, GalLDH, GLDase, GLDH, GLDH-A1, GLDH-B1, GLDH-D1, GLDH1, GLDHase, L-galactone-1,4-lactone dehydrogenase, L-galactono-1, 4-lactone dehydrogenase, L-galactono-1,4-lactone dehydrogenase, L-galactono-gamma-lactone dehydrogenase, L-GalLDH, L-GalLDH1, L-GalLDH2, LsL-GalLDH, RrGalLDH

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.2 With a cytochrome as acceptor
                1.3.2.3 L-galactonolactone dehydrogenase

Reference

Reference on EC 1.3.2.3 - L-galactonolactone dehydrogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mapson, L.W.; Breslow, E.
Properties of partially purified L-galactono-gamma-lactone dehydrogenase
Biochem. J.
65
29P
1957
Brassica oleracea var. botrytis
-
Manually annotated by BRENDA team
Oba, K.; Ishikawa, S.; Nishikawa, M.; Mizuno, H.; Yamamoto, T.
Purification and properties of L-galactono-gamma-lactone dehydrogenase, a key enzyme for ascorbic acid biosynthesis, from sweet potato roots
J. Biochem.
117
120-124
1995
Ipomoea batatas
Manually annotated by BRENDA team
Ostergaard, J.; Persiau, G.; Davey, M.W.; Bauw, G.; Van Montagu, M.
Isolation of a cDNA coding for L-galactono-gamma-lactone dehydrogenase, an enzyme involved in the biosynthesis of ascorbic acid in plants. Purification, characterization, cDNA cloning, and expression in yeast
J. Biol. Chem.
272
30009-30016
1997
Brassica oleracea var. botrytis (O47881), Brassica oleracea var. botrytis
Manually annotated by BRENDA team
Siendones, E.; Gonzalez-Reyes, J.A.; Santos-Ocana, C.; Navas, P.; Cordoba, F.
Biosynthesis of ascorbic acid in kidney bean. L-Galactono-gamma-lactone dehydrogenase is an intrinsic protein located at the mitochondrial inner membrane
Plant Physiol.
120
907-912
1999
Phaseolus vulgaris
Manually annotated by BRENDA team
Imai, T.; Karita, S.; Shiratori, G.; Hattori, M.; Nunome, T.; Oba, K.; Hirai, M.
L-Galactono-gamma-lactone dehydrogenase from sweet potato: purification and cDNA sequence analysis
Plant Cell Physiol.
39
1350-1358
1998
Ipomoea batatas
Manually annotated by BRENDA team
Yabuta, Y.; Yoshimura, K.; Takeda, T.; Shigeoka, S.
Molecular characterization of tobacco mitochondrial L-galactono-gamma-lactone dehydrogenase and its expression in Escherichia coli
Plant Cell Physiol.
41
666-675
2000
Nicotiana tabacum
Manually annotated by BRENDA team
Mutsuda, M.; Ishikawa, T.; Takeda, T.; Shigeoka, S.
Subcellular localization and properties of L-galactono-gamma-lactone dehydrogenase in spinach leaves
Biosci. Biotechnol. Biochem.
59
1983-1984
1995
Spinacia oleracea
-
Manually annotated by BRENDA team
Tudela, J.A.; Hernandez, J.A.; Gil, M.I.; Espin, J.C.
L-Galactono-gamma-lactone dehydrogenase and vitamin C content in fresh-cut potatoes stored under controlled atmospheres
J. Agric. Food Chem.
51
4296-4302
2003
Solanum tuberosum
Manually annotated by BRENDA team
Pateraki, I.; Sanmartin, M.; Kalamaki, M.S.; Gerasopoulos, D.; Kanellis, A.K.
Molecular characterization and expression studies during melon fruit development and ripening of L-galactono-1,4-lactone dehydrogenase
J. Exp. Bot.
55
1623-1633
2004
Cucumis melo (Q9M4U9)
Manually annotated by BRENDA team
Kostman, T.A.; Koscher, J.R.
L-Galactono-gamma-lactone dehydrogenase is present in calcium oxalate crystal idioblasts of two plant species
Plant Physiol. Biochem.
41
201-206
2003
Medicago truncatula, Pistia stratiotes
-
Manually annotated by BRENDA team
Tamaoki, M.; Mukai, F.; Asai, N.; Nakajima, N.; Kubo, A.; Aono, M.; Saji, H.
Light-controlled expression of a gene encoding L-galactono-gamma-lactone dehydrogenase which affects ascorbate pool size in Arabidopsis thaliana
Plant Sci.
164
1111-1117
2003
Arabidopsis thaliana
-
Manually annotated by BRENDA team
Bartoli, C.G.; Yu, J.; Gomez, F.; Fernandez, L.; McIntosh, L.; Foyer, C.H.
Inter-relationships between light and respiration in the control of ascorbic acid synthesis and accumulation in Arabidopsis thaliana leaves
J. Exp. Bot.
57
1621-1631
2006
Arabidopsis thaliana
Manually annotated by BRENDA team
Bartoli, C.G.; Guiamet, J.J.; Kiddle, G.; Pastori, G.M.; Di Cagno, R.; Theodoulou, F.L.; Foyer, C.H.
Ascorbate content of wheat leaves is not determined by maximal L-galactono-1,4-lactone dehydrogenase (GalLDH) activity under drought stress
Plant Cell Environ.
28
1073-1081
2005
Triticum aestivum
-
Manually annotated by BRENDA team
Groten, K.; Vanacker, H.; Dutilleul, C.; Bastian, F.; Bernard, S.; Carzaniga, R.; Foyer, C.H.
The roles of redox processes in pea nodule development and senescence
Plant Cell Environ.
28
1293-1304
2005
Pisum sativum
-
Manually annotated by BRENDA team
Song, X.S.; Tiao, C.L.; Shi, K.; Mao, W.H.; Ogweno, J.O.; Zhou, Y.H.; Yu, J.Q.
The response of antioxidant enzymes in cellular organelles in cucumber (Cucumis sativus L.) leaves to methyl viologen-induced photo-oxidative stress
Plant Growth Regul.
49
85-93
2006
Cucumis sativus
-
Manually annotated by BRENDA team
Matamoros, M.A.; Loscos, J.; Coronado, M.J.; Ramos, J.; Sato, S.; Testillano, P.S.; Tabata, S.; Becana, M.
Biosynthesis of ascorbic acid in legume root nodules
Plant Physiol.
141
1068-1077
2006
Lotus japonicus, Medicago sativa, Phaseolus vulgaris, Pisum sativum
Manually annotated by BRENDA team
Tokunaga, T.; Miyahara, K.; Tabata, K.; Esaka, M.
Generation and properties of ascorbic acid-overproducing transgenic tobacco cells expressing sense RNA for L-galactono-1,4-lactone dehydrogenase
Planta
220
854-863
2005
Nicotiana tabacum (Q9FXL9), Nicotiana tabacum
Manually annotated by BRENDA team
Oliveira do Nascimento, J.R.; Higuchi, B.K.; Gomez, M.L.; Oshiro, R.A.; Lajolo, F.M.
L-ascorbate biosynthesis in strawberries: L-Galactono-1,4-lactone dehydrogenase expression during fruit development and ripening
Postharvest Biol. Technol.
38
34-42
2005
Fragaria x ananassa (Q8L8A9)
-
Manually annotated by BRENDA team
Leferink, N.G.; van den Berg, W.A.; van Berkel, W.J.
L-galactono-gamma-lactone dehydrogenase from Arabidopsis thaliana, a flavoprotein involved in vitamin C biosynthesis
FEBS J.
275
713-726
2008
Arabidopsis thaliana
Manually annotated by BRENDA team
Yabuta, Y.; Mieda, T.; Rapolu, M.; Nakamura, A.; Motoki, T.; Maruta, T.; Yoshimura, K.; Ishikawa, T.; Shigeoka, S.
Light regulation of ascorbate biosynthesis is dependent on the photosynthetic electron transport chain but independent of sugars in Arabidopsis
J. Exp. Bot.
58
2661-2671
2007
Arabidopsis thaliana
Manually annotated by BRENDA team
Alhagdow, M.; Mounet, F.; Gilbert, L.; Nunes-Nesi, A.; Garcia, V.; Just, D.; Petit, J.; Beauvoit, B.; Fernie, A.R.; Rothan, C.; Baldet, P.
Silencing of the mitochondrial ascorbate synthesizing enzyme L-galactono-1,4-lactone dehydrogenase affects plant and fruit development in tomato
Plant Physiol.
145
1408-1422
2007
Solanum lycopersicum (Q8LP11), Solanum lycopersicum
Manually annotated by BRENDA team
Leferink, N.G.; Jose, M.D.; van den Berg, W.A.; van Berkel, W.J.
Functional assignment of Glu386 and Arg388 in the active site of L-galactono-gamma-lactone dehydrogenase
FEBS Lett.
583
3199-3203
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Pineau, B.; Layoune, O.; Danon, A.; De Paepe, R.
L-galactono-1,4-lactone dehydrogenase is required for the accumulation of plant respiratory complex I
J. Biol. Chem.
283
32500-32505
2008
Nicotiana sylvestris, Arabidopsis thaliana (Q9SU56), Arabidopsis thaliana
Manually annotated by BRENDA team
Leferink, N.G.; van Duijn, E.; Barendregt, A.; Heck, A.J.; van Berkel, W.J.
Galactonolactone dehydrogenase requires a redox-sensitive thiol for optimal production of vitamin C
Plant Physiol.
150
596-605
2009
Arabidopsis thaliana (Q9SU56), Arabidopsis thaliana
Manually annotated by BRENDA team
Imai, T.; Niwa, M.; Ban, Y.; Hirai, M.; Oba, K.; Moriguchi, T.
Importance of the L-galactonolactone pool for enhancing the ascorbate content revealed by L-galactonolactone dehydrogenase-overexpressing tobacco plants
Plant Cell Tissue Organ Cult.
96
105-112
2009
Ipomoea batatas
-
Manually annotated by BRENDA team
Liu, Y.; Yu, L.; Wang, R.
Level of ascorbic acid in transgenic rice for l-galactono-1,4-lactone dehydrogenase overexpressing or suppressed is associated with plant growth and seed set
Acta Physiol. Plant.
33
1353-1363
2011
Oryza sativa
-
Manually annotated by BRENDA team
Liu, W.; An, H.; Yang, M.
Overexpression of Rosa roxburghii L-galactono-1,4-lactone dehydrogenase in tobacco plant enhances ascorbate accumulation and abiotic stress tolerance
Acta Physiol. Plant.
35
1617-1624
2013
Rosa roxburghii (Q6DUK5)
-
Manually annotated by BRENDA team
Hervas, M.; Bashir, Q.; Leferink, N.G.; Ferreira, P.; Moreno-Beltran, B.; Westphal, A.H.; Diaz-Moreno, I.; Medina, M.; de la Rosa, M.A.; Ubbink, M.; Navarro, J.A.; van Berkel, W.J.
Communication between (L)-galactono-1,4-lactone dehydrogenase and cytochrome c
FEBS J.
280
1830-1840
2013
Arabidopsis thaliana
Manually annotated by BRENDA team
Schertl, P.; Sunderhaus, S.; Klodmann, J.; Grozeff, G.E.; Bartoli, C.G.; Braun, H.P.
L-galactono-1,4-lactone dehydrogenase (GLDH) forms part of three subcomplexes of mitochondrial complex I in Arabidopsis thaliana
J. Biol. Chem.
287
14412-14419
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Liu, Y.; Yu, L.; Tong, J.; Ding, J.; Wang, R.; Lu, Y.; Xiao, L.
Tiller number is altered in the ascorbic acid-deficient rice suppressed for L-galactono-1,4-lactone dehydrogenase
J. Plant Physiol.
170
389-396
2013
Oryza sativa
Manually annotated by BRENDA team
Guo, X.; Liu, R.; Fu, X.; Sun, X.; Tang, K.
Over-expression of L-galactono-gamma-lactone dehydrogenase increases vitamin C, total phenolics and antioxidant activity in lettuce through bio-fortification
Plant Cell Tissue Organ Cult.
114
225-236
2013
Oryza sativa
-
Manually annotated by BRENDA team
Zsigmond, L.; Tomasskovics, B.; Deak, V.; Rigo, G.; Szabados, L.; Banhegyi, G.; Szarka, A.
Enhanced activity of galactono-1,4-lactone dehydrogenase and ascorbate-glutathione cycle in mitochondria from complex III deficient Arabidopsis
Plant Physiol. Biochem.
49
809-815
2011
Arabidopsis thaliana
Manually annotated by BRENDA team
Yu, L.; Liu, Y.; Lu, L.; Zhang, Q.; Chen, Y.; Zhou, L.; Chen, H.; Peng, C.
Ascorbic acid deficiency leads to increased grain chalkiness in transgenic rice for suppressed of L-GalLDH
J. Plant Physiol.
211
13-26
2017
Oryza sativa Japonica Group (Q2QXY1), Oryza sativa Japonica Group (Q2RAP0)
Manually annotated by BRENDA team
Landi, M.; Fambrini, M.; Basile, A.; Salvini, M.; Guidi, L.; Pugliesi, C.
Overexpression of L-galactono-1,4-lactone dehydrogenase (L-GalLDH) gene correlates with increased ascorbate concentration and reduced browning in leaves of Lactuca sativa L. after cutting
Plant Cell Tissue Organ Cult.
123
109-120
2015
Lactuca sativa (W6N8V9)
-
Manually annotated by BRENDA team
Li, B.; Yang, Y.; Yu, C.; Li, S.; Chen, J.; Liu, X.; Qin, H.; Wang, D.
Partial suppression of L-galactono-1,4-lactone dehydrogenase causes significant reduction in leaf water loss through decreasing stomatal aperture size in Arabidopsis
Plant Growth Regul.
72
171-179
2014
Arabidopsis thaliana (Q9SU56), Arabidopsis thaliana Col-0 (Q9SU56)
-
Manually annotated by BRENDA team
Schimmeyer, J.; Bock, R.; Meyer, E.H.
L-Galactono-1,4-lactone dehydrogenase is an assembly factor of the membrane arm of mitochondrial complex I in Arabidopsis
Plant Mol. Biol.
90
117-126
2016
Arabidopsis thaliana (Q9SU56), Arabidopsis thaliana Col-0 (Q9SU56)
Manually annotated by BRENDA team
Rodriguez-Ruiz, M.; Mateos, R.M.; Codesido, V.; Corpas, F.J.; Palma, J.M.
Characterization of the galactono-1,4-lactone dehydrogenase from pepper fruits and its modulation in the ascorbate biosynthesis. Role of nitric oxide
Redox Biol.
12
171-181
2017
Capsicum annuum (Q6QD76)
Manually annotated by BRENDA team
Zhang, J.; Li, B.; Yang, Y.; Mu, P.; Qian, W.; Dong, L.; Zhang, K.; Liu, X.; Qin, H.; Ling, H.; Wang, D.
A novel allele of L-galactono-1,4-lactone dehydrogenase is associated with enhanced drought tolerance through affecting stomatal aperture in common wheat
Sci.Rep.
6
30177
2016
Triticum aestivum (A0A1B1X3I2), Triticum aestivum (W5FJN8), Triticum aestivum (W5FUB4), Triticum aestivum
Manually annotated by BRENDA team
Zhou, H.; Milne, R.; Ma, X.; Song, Y.; Fang, J.; Sun, H.; Zha, H.
Characterization of a L-gulono-1,4-lactone oxidase like protein in the floral nectar of Mucuna sempervirens, fabaceae
Front. Plant Sci.
9
1109
2018
Mucuna sempervirens
Manually annotated by BRENDA team
Zheng, X.; Zhang, X.; Wang, Y.; Cai, M.; Li, M.; Zhang, T.; Peng, C.
Identification of a GLDH-overexpressing arabidopsis mutant and its responses to high-light stress
Photosynthetica
57
332-341
2019
Arabidopsis thaliana
-
Manually annotated by BRENDA team