1.3.1.94: polyprenol reductase

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For detailed information about polyprenol reductase, go to the full flat file.

Reaction

Synonyms

DFG10, PPRD, SDR5A3, SRD5A3, steroid 5alpha-reductase type 3

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.94 polyprenol reductase

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2985	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
49	Disease/ Diagnostics
3	General Information
1	Localization
3	Natural Substrates/ Products (Substrates)
5	Organism
5	Pathway
1	pH Optimum
1	Reaction
5	Reference
1	Source Tissue
7	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.3.1.94 - polyprenol reductase

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SYSTEMATIC NAME

IUBMB Comments

ditrans,polycis-dolichol:NADP+ 2,3-oxidoreductase

The reaction occurs in the reverse direction with reduction of the terminal double bond next to the alcohol group. Isolated from human fetal brain tissue but present in all eukaryotes. In mammalian cells dolichols are predominantly 18-21 isoprene units in length.