1.3.1.85: crotonyl-CoA carboxylase/reductase
This is an abbreviated version!
For detailed information about crotonyl-CoA carboxylase/reductase, go to the full flat file.
Word Map on EC 1.3.1.85
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1.3.1.85
-
polyketide
-
rhodobacter
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acyl-coas
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glyoxylate
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sphaeroides
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propionyl-coa
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3-hydroxypropionate
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extorquens
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methylobacterium
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butyryl-coa
- 1.3.1.85
- polyketide
-
rhodobacter
- acyl-coas
- glyoxylate
- sphaeroides
- propionyl-coa
- 3-hydroxypropionate
- extorquens
-
methylobacterium
- butyryl-coa
Reaction
Synonyms
2-octenoyl-CoA carboxylase/reductase, AntE, CCR, CCR1, CCRC, crotonyl-CoA carboxylase/reductase, crotonyl-CoA reductase (carboxylating), crotonyl-CoA reductase-carboxylase, ECR, enoyl-CoA carboxylase/reductase, pteB, rimJ
ECTree
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Systematic Name
Systematic Name on EC 1.3.1.85 - crotonyl-CoA carboxylase/reductase
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(2S)-ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating)
The reaction is catalysed in the reverse direction. This enzyme, isolated from the bacterium Rhodobacter sphaeroides, catalyses (E)-but-2-enoyl-CoA-dependent oxidation of NADPH in the presence of CO2. When CO2 is absent, the enzyme catalyses the reduction of (E)-but-2-enoyl-CoA to butanoyl-CoA, but with only 10% of maximal activity (relative to (E)-but-2-enoyl-CoA carboxylation).