1.3.1.8: acyl-CoA dehydrogenase (NADP+)

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For detailed information about acyl-CoA dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.3.1.8

1.3.1.8

enoyl-coas

acyl-coas

crotonyl-coa

very-long-chain

vlcfas

butyryl-coa

dehydrase

3-hydroxyacyl-coa

beta-hydroxyacyl-coa

decanoyl-coa

acetyl-coa-dependent

octanoyl-coa

elongase

leek

nadph-specific

collinus

trans-enoyl-coas

synthesis

biotechnology

Reaction

Synonyms

2-enoyl-CoA reductase, 2-trans enoyl-CoA reductase, 2-trans-enoyl-CoA reductase, acyl coenzyme A dehydrogenase (nicotinamide adenine dinucleotide phosphate), CCR, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate), enoyl coenzyme A reductase, enoyl-CoA reductase, MCAD, medium-chain acyl-CoA dehydrogenase, NADPH:enoyl-CoA oxidoreductase, NbECR, RCCR, trans-2-enoyl-CoA reductase

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.8 acyl-CoA dehydrogenase (NADP+)

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Results	in table
3	Activating Compound
15	AA Sequence
2	Application
1	CAS Registry Number
3	Cloned(Commentary)
33	Cofactor
1	Crystallization (Commentary)
1	General Stability
31	Inhibitors
4	Ki Value [mM]
18	KM Value [mM]
20	Localization
9	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
32	Organism
1	Oxidation Stability
5	Pathway
4	PDB ID
8	pH Optimum
1	pH Range
1	Protein Variants
10	Purification (Commentary)
2	Reaction
4	Reaction Type
30	Reference
26	Source Tissue
18	Specific Activity [micromol/min/mg]
3	Storage Stability
102	Substrates and Products (Substrate)
3	Subunits
22	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 1.3.1.8 - acyl-CoA dehydrogenase (NADP+)

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acyl-CoA:NADP+ 2-oxidoreductase

The liver enzyme acts on enoyl-CoA derivatives of carbon chain length 4 to 16, with optimum activity on 2-hexenoyl-CoA. In Escherichia coli, cis-specific and trans-specific enzymes exist [EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) and EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)].