1.3.1.77: anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

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For detailed information about anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming], go to the full flat file.

Reaction

Synonyms

ANR, ANR1, ANR1-2, ANR1-3, ANR2, ANR2a, ANRa, ANRb, anthocyanidin reductase, anthocyanidin reductase 1, anthocyanidin reductase 2, AtANR, BAN, BANYULS, BEN1, BpANR, CsANR, CsANR1, CsANR2, CssANRa, CssANRb, dihydroflavonol 4-reductase-like protein, FeANR, GhANR1, MdLAR1, MtANR, PtrANR1, RrANR, VbANR

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

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Results	in table
66	AA Sequence
1	Application
1	CAS Registry Number
41	Cloned(Commentary)
30	Cofactor
9	Expression
39	General Information
10	Inhibitors
8	kcat/KM [mM/s]
31	KM Value [mM]
4	Localization
3	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
78	Organism
5	Pathway
3	PDB ID
10	pH Optimum
2	pH Range
4	pI Value
8	Protein Variants
6	Purification (Commentary)
1	Reaction
5	Reaction Type
69	Reference
102	Source Tissue
95	Substrates and Products (Substrate)
8	Subunits
102	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
16	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.3.1.77 - anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

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SYSTEMATIC NAME

IUBMB Comments

(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase

The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].