1.3.1.28: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
This is an abbreviated version!
For detailed information about 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, go to the full flat file.
Word Map on EC 1.3.1.28
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1.3.1.28
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enterobactin
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nad+-dependent
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entb
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siderophore
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isochorismate
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chorismate
- 1.3.1.28
- enterobactin
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nad+-dependent
- entb
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siderophore
- isochorismate
- chorismate
Reaction
Synonyms
2,3-DHB dehydrogenase, 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase, cbxG, Cold shock protein CSI14, dehydrogenase, 2,3-dihydro-2,3-dihydroxybenzoate, EC 1.1.1.109, EntA
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Substrates Products
Substrates Products on EC 1.3.1.28 - 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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REACTION DIAGRAM
3-hydroxy-4-cyclohexene-1-carboxylate
3-oxo-4-cyclohexene-1-carboxylate + NADH
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reversible only with 3-keto compounds, not with 2-keto compounds
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r
4-trifluoromethyl-2,3-dihydro-2,3-dihydroxybenzoate + NAD+
4-trifluoromethyl-2,3-dihydroxybenzoate + NADH
cis-3-hydroxy-4-cyclohexene-1-carboxylate + NAD+
3-oxo-4-cyclohexene-1-carboxylate + NADH + H+
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-
-
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r
cis-3-hydroxy-cyclohexane-1-carboxylate + NAD+
3-oxo-cyclohexane-1-carboxylate + NADH
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-
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r
methyl-2,3-dihydro-3-hydroxybenzoate + NAD+
3-hydroxybenzoate + NADH
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-
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r
methyl-3-hydroxy-1,4-cyclohexadien-1-carboxylate + NAD+
3-hydroxybenzoate + NADH
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-
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r
trans-3-hydroxy-cyclohexane-1-carboxylate + NAD+
3-oxo-cyclohexane-1-carboxylate + NADH
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-
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r
trans-3-hydroxycyclohexane-1-carboxylic acid + NAD+
3-oxo-cyclohexane-1-carboxylate + NADH + H+
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-
-
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r
2,3-dihydroxybenzoate + NADH + H+
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-
-
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r
(2S,3S)-2,3-dihydro-2,3-dihydroxybenzoate + NAD+
2,3-dihydroxybenzoate + NADH + H+
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-
-
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?
4-trifluoromethyl-2,3-dihydroxybenzoate + NADH
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low turnover
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?
4-trifluoromethyl-2,3-dihydro-2,3-dihydroxybenzoate + NAD+
4-trifluoromethyl-2,3-dihydroxybenzoate + NADH
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low turnover
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?
2,3-dihydroxybenzoate + NADH
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-
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ir
trans-2,3-dihydro-2,3-dihydroxybenzoate + NAD+
2,3-dihydroxybenzoate + NADH
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genetic results suggest that the enzyme may also have isochorismate synthase activity
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?