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1.3.1.12: prephenate dehydrogenase

This is an abbreviated version!
For detailed information about prephenate dehydrogenase, go to the full flat file.

Word Map on EC 1.3.1.12

Reaction

prephenate
+
NAD+
=
4-hydroxyphenylpyruvate
 +
CO2
 +
NADH
 +
H+

Synonyms

AceF, AroQ, bifunctional T-protein, chorismate mutase-prephenate dehydratase, chorismate mutase-prephenate dehydrogenase bifunctional enzyme, chorismate mutase-T:prephenate dehydrogenase bifunctional enzyme, Chorismate mutase/prephenate dehydratase, CM-PD, CM-TyrAp, CM/PDT/PDHG, CMPD, dehydrogenase, prephenate, hydroxyphenylpyruvate synthase, PD, PDH, pdhE-1, PDHG, T-protein, TYR1, tyrA, TyrA dehydrogenase, TyrAp

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.12 prephenate dehydrogenase

KI Value

KI Value on EC 1.3.1.12 - prephenate dehydrogenase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.17
2-hydroxyphenylacetate
-
pH 7.8, 37°C
0.13 - 0.4
4-hydroxyphenylpyruvate
0.11
5,6-dihydro-5,6-dihydroxychorismate
-
pH 7.8, 37°C
0.15
adamantane-1,3-diacetate
-
pH 7.8, 37°C
0.13
adamantane-1-acetate
-
pH 7.8, 37°C
0.31
adamantane-1-carboxylate
-
pH 7.8, 37°C
0.14
adamantane-1-phosphonate
-
pH 7.8, 37°C
0.13
chorismate-5,6-epoxide
-
pH 7.8, 37°C
0.59
CKTENMQSC
-
pH 7.8, 37°C
0.2
coumaric acid
-
-
1.3
D-tyrosine
-
-
0.47
dihydroxyphenylalanine
-
-
0.3
L-phenylalanine
-
-
0.7
L-tryptophan
-
-
0.0015 - 5.5
L-tyrosine
0.21
trans-2,3-pleiadanedicarboxylic acid
-
pH 7.8, 37°C
0.0159 - 0.37
tyrosine