1.21.99.5: tetrachloroethene reductive dehalogenase
This is an abbreviated version!
For detailed information about tetrachloroethene reductive dehalogenase, go to the full flat file.
Word Map on EC 1.21.99.5
-
1.21.99.5
-
dechlorination
-
dehalococcoides
-
chlorinate
-
dehalogenation
-
mccartyi
-
bioremediation
-
organohalide
-
desulfitobacterium
-
vinyl
-
organohalide-respiring
-
groundwater
-
dehalobacter
-
rdhas
-
corrinoids
-
cis-1,2-dichloroethene
-
hafniense
-
multivorans
-
bioaugmentation
-
sulfurospirillum
-
microcosm
-
chloroflexi
-
restrictus
-
ethenogenes
-
dehalorespiration
-
cis-dce
-
aquifer
-
chlorophenols
-
cpras
-
cis-dichloroethene
-
geobacter
-
debromination
-
cobamide
-
dehalogenans
-
2,4,6-trichlorophenol
-
epsilonproteobacterium
-
1,1,2-trichloroethane
-
1,1-dichloroethane
-
analysis
-
1,2-dichloropropane
-
agriculture
- 1.21.99.5
-
dechlorination
- dehalococcoides
-
chlorinate
-
dehalogenation
- mccartyi
-
bioremediation
-
organohalide
- desulfitobacterium
-
vinyl
-
organohalide-respiring
-
groundwater
- dehalobacter
-
rdhas
- corrinoids
- cis-1,2-dichloroethene
- hafniense
- multivorans
-
bioaugmentation
- sulfurospirillum
-
microcosm
- chloroflexi
- restrictus
- ethenogenes
-
dehalorespiration
-
cis-dce
-
aquifer
- chlorophenols
-
cpras
- cis-dichloroethene
- geobacter
-
debromination
- cobamide
- dehalogenans
- 2,4,6-trichlorophenol
-
epsilonproteobacterium
- 1,1,2-trichloroethane
- 1,1-dichloroethane
- analysis
- 1,2-dichloropropane
- agriculture
Reaction
Synonyms
1,2,4,5-TeCB reductive dehalogenase, dceA6, dehalogenase, polychloroethene, EC 1.97.1.8, mbrA, PCE dehalogenase, PCE reductase, PCE reductive dehalogenase, PCE-dechlorinating enzyme, PCE-RD, PCE-RDase, PCE-reductive dehalogenase, PCE/PCB RDase, PCE/TCERD, PceA, pceA gene product, PceA1, PceA2, PceATCE, PceC, pceC gene product, PCER, PCERD, perchloroethylene dehalogenase, polychloroethane dehalogenase, RD11, RD8, RDase, RDH, RdhA, RdhA3, reductive dehalogenase, reductive PCE dehalogenase, Ssed_3769, TcbA, TCE dehalogenase, TCE reductase, tetrachlorobenzene dehalogenase, tetrachloroethene (PCE) dehalogenase, tetrachloroethene (PCE) reductive dehalogenase, tetrachloroethene and trichloroethene dehalogenase, tetrachloroethene dehalogenase, tetrachloroethene reductase, tetrachloroethene reductive dehalogenase, tetrachloroethene reductive dehalogenase catalytic subunit PceA, tetrachloroethylene reductase, ThMA, trichloroethene dehalogenase
ECTree
1.21.99.5 tetrachloroethene reductive dehalogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.21.99.5 - tetrachloroethene reductive dehalogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
1,1,1-trichloroethane + reduced acceptor
1,1-dichloroethane + chloride + acceptor
Dehalobacter sp. THM1
-
-
-
?
1,1,2-trichloroethane + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
1,1,3-trichloro-1-propene + Ti(III) citrate
1,1-dichloro-1-propene + Cl- + ?
-
-
-
-
?
1,1,3-trichloropropene + reduced acceptor
1,1-dichloropropene + chloride + acceptor
-
22.9% activity compared with perchloroethene as substrate
-
-
?
1,1-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
1,2,4,5-tetrachlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
1,2,4,5-tetrachlorobenzene + reduced methyl viologen
1,2,4-trichlorobenzene + chloride + methyl viologen
-
-
-
-
?
1,2,4-trichlorobenzene + reduced acceptor
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor
-
-
-
-
?
1,2,4-trichlorobenzene + reduced methyl viologen
1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + methyl viologen
-
-
-
-
?
1,2-dichloropropane + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,3-dichloro-1-propene + Ti(III) citrate
2-chloropropene + Cl- + ?
-
as a side product, 2,5-dichloro-1,5-hexadiene is formed demonstrating that the reductive dechlorination of 2,3-dichloropropene proceeds via a radical reaction mechanism
-
-
?
2,3-dichloropropene + reduced acceptor
2-chloropropene + chloride + acceptor
-
14.4% activity compared with perchloroethene as substrate
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
3,5-dichlorophenol + reduced acceptor
? + chloride + oxidized acceptor
-
-
-
?
chlorinated propenes + reduced acceptor
propene + chloride + acceptor
-
22% of the reduction rates with perchloroethene
-
-
?
chloroacetamide + reduced acceptor
acetamide + chloride + acceptor
-
very poor substrate
-
-
?
chloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
cis-1,2-dichloroethene + reduced acceptor
monochloroethene + chloride + acceptor
-
-
-
-
?
cis-1,2-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
cis-1,3-dichloropropene + reduced acceptor
mono-chloropropene + chloride + acceptor
-
chlorination rate is lower than for trans-1,3-dichloropropene and reaction ceases after 2-3 min
-
?
dichloroethene + reduced acceptor
chloroethene + chloride + acceptor
-
-
-
-
?
hexachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
monochloroethene + reduced acceptor
ethene + chloride + acceptor
-
-
-
-
?
pentachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + 2 H2
cis-1,2-dichloroethene + 2 chloride + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
tetrachloroethene + reduced benzylviologen
trichloroethene + chloride + benzylviologen
-
-
-
-
?
tetrachloroethene + reduced cobaltocene
trichloroethene + chloride + cobaltocene
-
-
-
-
?
tetrachloroethene + reduced ethyl viologen
cis-1,2-dichloroethene + chloride + ethyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
trichloroethene + chloride + methyl viologen
-
-
-
?
tetrachloromethane + reduced acceptor
? + chloride + acceptor
-
very poor substrate
-
-
?
tetraiodoethene + reduced acceptor
triiodoethene + iodide + acceptor
-
reaction rate is considerably slower than with tetrachloroethene
-
-
?
trans-1,2-dichloroethylene + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
trans-1,3-dichloropropene + reduced acceptor
mono-chloropropene + chloride + acceptor
-
5.7% activity compared with perchloroethene as substrate
-
?
trichloroethene + reduced acceptor
dichloroethene + chloride + acceptor
-
-
-
-
?
1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
-
-
-
-
?
1,1,1,2,2,3,3-heptachloropropane + reduced acceptor
1,1,2,3,3,3-hexachloroprop-1-ene + chloride + acceptor
-
-
-
-
?
1,1,1,2-tetrachloroethane + reduced acceptor
1,1-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,1,2-tetrachloroethane + reduced acceptor
1,1-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2,2-tetrachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2,2-tetrachloroethane + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2-trichloroethene + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
1,1,2-trichloroethene + reduced acceptor
cis-1,2-dichlorethene + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor
? + chloride + acceptor
-
-
-
-
?
2,3-dichlorophenol + reduced acceptor
2-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,3-dichlorophenol + reduced acceptor
2-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,5-trichlorophenol + reduced acceptor
3,4-dichlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,6-trichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4,6-trichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4-dichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
2,4-dichlorophenol + reduced acceptor
4-chlorophenol + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
terminal component of the respiratory chain
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
-
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
-
via trichloroethene, enables growth on tetrachloroethene as sole energy source
-
-
?
tetrachloroethene + 2 reduced acceptor
cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+
Sulfurospirillum multivorans DSMZ 12446
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
cis-1,2-dichlorethene + 2 chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trans-1,2 dichloroethene + acceptor + 2 chloride
dechlorination activity of tetrachloroethene to trans-1,2 dichloroethene is detected after 24 h of incubating the corresponding unstained gel fragment
-
-
?
tetrachloroethene + reduced acceptor
trans-1,2 dichloroethene + acceptor + 2 chloride
dechlorination activity of tetrachloroethene to trans-1,2 dichloroethene is detected after 24 h of incubating the corresponding unstained gel fragment
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
lipophilic solvent tetrachloroethene, one of the most abundant halogenated xenobiotic pollutants in the environment
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
quite specific for tetrachloroethene
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
besides reduced methyl viologen, titanium(III)citrate can serve as electron donor for reductive dehalogenation
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
perchloroethylene, perchloroethene, PCE
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
PCE, physiological electron donor is not known
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced acceptor
trichloroethene + chloride + oxidized acceptor
-
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
via trichloroethene
-
-
?
tetrachloroethene + reduced methyl viologen
cis-1,2-dichloroethene + 2 chloride + methyl viologen
-
via trichloroethene
-
-
?
tetrachloroethene + reduced methylviologen
trichloroethene + chloride + methylviologen
-
-
-
-
?
tetrachloroethene + reduced methylviologen
trichloroethene + chloride + methylviologen
-
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + chloride + acceptor
tetrachloroethene + reduced acceptor
-
-
-
-
?
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
?
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
-
r
trichloroethene + chloride + methyl viologen
tetrachloroethene + reduced methyl viologen
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
good substrate, comparable to tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
70% of activity compared with tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
good substrate, comparable to tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
poor substrate, 10% of the rate of tetrachloroethene
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
-
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
artificial electron donor: reduced methyl viologen, physiological electron donor is not known
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
besides reduced methyl viologen, titanium(III)citrate can serve as electron donor for reductive dehalogenation
-
-
?
trichloroethene + reduced acceptor
cis-1,2-dichloroethene + chloride + acceptor
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
physiological electron donor is not known
-
-
?
additional information
?
-
-
PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond
-
-
?
additional information
?
-
trichlofluoroethene, tetrachloromethane, hexachloroethane, tetrachloroethane, trichloroethane, and 1,1,1-trichloro-2,2,2-trifluoroethane cause an enzyme dependent oxidation of reduced methyl viologen
-
-
?
additional information
?
-
-
trichlofluoroethene, tetrachloromethane, hexachloroethane, tetrachloroethane, trichloroethane, and 1,1,1-trichloro-2,2,2-trifluoroethane cause an enzyme dependent oxidation of reduced methyl viologen
-
-
?
additional information
?
-
-
no activity with trichloroethene, TCE, cis-dichloroethene, cis-DCE, or vinyl chloride
-
-
?
additional information
?
-
-
very low activity with reduced benzyl viologen
-
-
?
additional information
?
-
-
no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
-
-
?
additional information
?
-
-
very high substrate specificity
-
-
?
additional information
?
-
-
no activity with other chloroethenes or chloromethanes or chlorinated aromatic compounds, no activity with carbon tetrachloride, 1,1-dichloroethene, trans-1,2-dichloroethene, cis-1,2-dichloroethene, 3-chlorobenzoate, 3-chloro-4-hydroxyphenol, pentachlorophenol, 2,4,6-trichlorophenol, 2,4,5-trichlorophenol
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
-
-
the enzyme shows no dihaloelimination activity towards 1,1,2-trichloroethane or 1,1,1-trichloroethane
-
-
?
additional information
?
-
no substrates: 2,6-dichlorophenol, 3,4-dichlorophenol
-
-
?
additional information
?
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-
no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
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additional information
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the enzyme shows no dihaloelimination activity towards 1,1,2-trichloroethane or 1,1,1-trichloroethane
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additional information
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no activity with 3-chloro-4-hydroxyphenylacetate and other ortho-chlorophenolic compounds, 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,3-dichlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, cis-dichloroethene
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additional information
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broad substrate specificity, degrades various chlorinated aliphatic compounds
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additional information
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broad substrate specificity, degrades various chlorinated aliphatic compounds
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additional information
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physiological electron donor is not known
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additional information
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no activity with other chloroethenes, chloroethanes or chloromethanes, no activity with 1,1-dichloroethene, trans-1,2-dichloroethene, 1,1,1-trichloroethane, 1,1,1-trichloroacetone, hexachloroethane, and the chlorinated aromatic compounds 3-chlorobenzoate, 4-chlorophenol, and 3,4-dichlorobenzoate
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additional information
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no activity with dichloroethene, 1-chloropropene, 2-chloropropene, 3-chloropropene, 1,1-dichloropropene, 1,2-dichloropropane, 1,3-dichloropropane, and 1,2,3-trichloropropane
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additional information
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anaerobic growth in presence of dimethylbenzimidazole leads to replacement of the adenine moiety in the nucleotide loop of cofoactor norpseudo-B12 by dimethylbenzimidazole. The formation of the dimethylbenzimidazole-containing nor-B12 severely affects tetrachloroethene-dependent growth and the PceA activity. In dimethylbenzimidazole-treated cells processing of the cytoplasmic PceA precursor is impeded. PceA enriched from cells cultivated with dimethylbenzimidazole contains nor-B12. Nor-B12 purified from cells grown in the presence of dimethylbenzimidazole mediates the abiotic reductive dehalogenation of trichloroacetate to dichloroacetate at a 25fold lower rate in comparison with norpseudo-B12
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additional information
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dehalogenation of tetrachloroethene results in a similar extent of C and Cl isotope fractionation, and in similar dual element isotope slopes for PceA enzyme and for abiotic dehylogenation by corrinoids. Catalytic dehalogenation by enzymes and different corrinoids display mechanistic and/or kinetic differences
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additional information
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anaerobic growth in presence of dimethylbenzimidazole leads to replacement of the adenine moiety in the nucleotide loop of cofoactor norpseudo-B12 by dimethylbenzimidazole. The formation of the dimethylbenzimidazole-containing nor-B12 severely affects tetrachloroethene-dependent growth and the PceA activity. In dimethylbenzimidazole-treated cells processing of the cytoplasmic PceA precursor is impeded. PceA enriched from cells cultivated with dimethylbenzimidazole contains nor-B12. Nor-B12 purified from cells grown in the presence of dimethylbenzimidazole mediates the abiotic reductive dehalogenation of trichloroacetate to dichloroacetate at a 25fold lower rate in comparison with norpseudo-B12
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additional information
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dehalogenation of tetrachloroethene results in a similar extent of C and Cl isotope fractionation, and in similar dual element isotope slopes for PceA enzyme and for abiotic dehylogenation by corrinoids. Catalytic dehalogenation by enzymes and different corrinoids display mechanistic and/or kinetic differences
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additional information
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no substrate: trichloroethene
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additional information
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in homogeneous aqueous solution containing titanium(III) citrate or titanium(III)-nitrilotriacetic acid as bulk electron donor, cobalamin, cobinamide, and cobamide are effective electron transfer mediators for the reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene. For a given chlorinated ethene, the reaction rate varies only slightly with pH and type of corrinoid present and is about 5 and 50 times faster for tetrachloroethene as compared to trichlorofluoroethene and trichloroethene, respectively. The first and rate-limiting step of the reduction of tetrachloroethene, trichloroethene, and trichlorofluoroethene by super-reduced corrinoids is a dissociative one-electron transfer yielding the corresponding vinyl radicals
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additional information
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using pull-down assays PceA1 interacts with DnaK (Hsp70)
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additional information
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using pull-down assays PceA1 interacts with DnaK (Hsp70)
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