1.21.99.5: tetrachloroethene reductive dehalogenase

This is an abbreviated version!
For detailed information about tetrachloroethene reductive dehalogenase, go to the full flat file.

Reaction

Synonyms

1,2,4,5-TeCB reductive dehalogenase, dceA6, dehalogenase, polychloroethene, EC 1.97.1.8, mbrA, PCE dehalogenase, PCE reductase, PCE reductive dehalogenase, PCE-dechlorinating enzyme, PCE-RD, PCE-RDase, PCE-reductive dehalogenase, PCE/PCB RDase, PCE/TCERD, PceA, pceA gene product, PceA1, PceA2, PceATCE, PceC, pceC gene product, PCER, PCERD, perchloroethylene dehalogenase, polychloroethane dehalogenase, RD11, RD8, RDase, RDH, RdhA, RdhA3, reductive dehalogenase, reductive PCE dehalogenase, Ssed_3769, TcbA, TCE dehalogenase, TCE reductase, tetrachlorobenzene dehalogenase, tetrachloroethene (PCE) dehalogenase, tetrachloroethene (PCE) reductive dehalogenase, tetrachloroethene and trichloroethene dehalogenase, tetrachloroethene dehalogenase, tetrachloroethene reductase, tetrachloroethene reductive dehalogenase, tetrachloroethene reductive dehalogenase catalytic subunit PceA, tetrachloroethylene reductase, ThMA, trichloroethene dehalogenase

ECTree

     1 Oxidoreductases

         1.21 Catalysing the reaction X-H + Y-H = X-Y

             1.21.99 With unknown physiological acceptors

                1.21.99.5 tetrachloroethene reductive dehalogenase

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Results	in table
2	Activating Compound
39	AA Sequence
9	Application
2	CAS Registry Number
5	Cloned(Commentary)
26	Cofactor
5	Expression
5	General Information
9	General Stability
49	Inhibitors
29	KM Value [mM]
28	Localization
69	Metals/Ions
26	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
84	Organism
1	Oxidation Stability
4	Pathway
12	pH Optimum
1	pH Range
4	pH Stability
5	Posttranslational Modification
16	Protein Variants
11	Purification (Commentary)
13	Reaction
5	Reaction Type
56	Reference
1	Renatured (Commentary)
11	Specific Activity [micromol/min/mg]
1	Storage Stability
173	Substrates and Products (Substrate)
24	Subunits
73	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
2	Temperature Stability [°C]
2	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.21.99.5 - tetrachloroethene reductive dehalogenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

1,2,4,5-tetrachlorobenzene + reduced acceptor

1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor

Dehalobacter sp. TeCB1

-

-

744981

-

-

?

1,2,4-trichlorobenzene + reduced acceptor

1,3-dichlorobenzene + 1,4-dichlorobenzene + chloride + acceptor

Dehalobacter sp. TeCB1

-

-

744981

-

-

?

2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor

? + chloride + acceptor

2 entries

chloroethene + reduced acceptor

ethene + chloride + acceptor

Dehalococcoides sp. YN3

-

-

744468

-

-

?

cis-1,2-dichloroethene + reduced acceptor

monochloroethene + chloride + acceptor

Dehalococcoides mccartyi

-

-

746490

-

-

?

dichloroethene + reduced acceptor

chloroethene + chloride + acceptor

Dehalococcoides sp. YN3

-

-

744468

-

-

?

monochloroethene + reduced acceptor

ethene + chloride + acceptor

Dehalococcoides mccartyi

-

-

746490

-

-

?

tetrachloroethene + 2 H2

cis-1,2-dichloroethene + 2 chloride + 2 H+

Dehalococcoides mccartyi

-

via trichloroethene, enables growth on tetrachloroethene as sole energy source

657605

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

7 entries

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

13 entries

trichloroethene + chloride + acceptor

tetrachloroethene + reduced acceptor

2 entries

trichloroethene + reduced acceptor

cis-1,2-dichloroethene + chloride + acceptor

3 entries

trichloroethene + reduced acceptor

dichloroethene + chloride + acceptor

Dehalococcoides sp. YN3

-

-

744468

-

-

?

additional information

?

-

3 entries

2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor

? + chloride + acceptor

Dehalococcoides mccartyi

-

-

744800

-

-

?

2,2',3,4,4',5,5'-heptachlorobiphenyl + reduced acceptor

? + chloride + acceptor

Dehalococcoides mccartyi JNA

-

-

744800

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Dehalobacter restrictus

Q8GJ27

terminal component of the respiratory chain

657587

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Desulfitobacterium hafniense

-

-

744925

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Desulfitobacterium hafniense

Q8GJ31

terminal component of the respiratory chain

657587

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Desulfitobacterium hafniense Y51

-

-

744925

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Sulfurospirillum multivorans

-

-

744924

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Sulfurospirillum multivorans

-

via trichloroethene, enables growth on tetrachloroethene as sole energy source

657689

-

-

?

tetrachloroethene + 2 reduced acceptor

cis-1,2-dichloroethene + 2 chloride + 2 acceptor + 2 H+

Sulfurospirillum multivorans DSMZ 12446

-

-

744924

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalobacter restrictus

-

-

349702

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalobacter restrictus

-

PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond

349701

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalococcoides mccartyi

-

-

349703, 744800, 746490

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalococcoides mccartyi JNA

-

-

744800

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalococcoides sp.

-

-

744798

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Dehalococcoides sp. YN3

-

-

744468

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Desulfitobacterium hafniense

-

-

349705, 349706

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Desulfitobacterium hafniense TCE1

-

-

349705

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Desulfitobacterium sp. PCE1

-

-

349705

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Paraclostridium bifermentans

-

-

349709

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Paraclostridium bifermentans DPH-1

-

-

349709

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Sulfurospirillum multivorans

-

-

349704, 349707, 349708

-

-

?

tetrachloroethene + reduced acceptor

trichloroethene + chloride + acceptor

Sulfurospirillum multivorans

-

PCE, physiological electron donor is not known

349700

-

-

?

trichloroethene + chloride + acceptor

tetrachloroethene + reduced acceptor

Desulfitobacterium hafniense

-

-

744884

-

-

?

trichloroethene + chloride + acceptor

tetrachloroethene + reduced acceptor

Desulfitobacterium hafniense Y51

-

-

744884

-

-

?

trichloroethene + reduced acceptor

cis-1,2-dichloroethene + chloride + acceptor

Dehalobacter restrictus

-

-

349701

-

-

?

trichloroethene + reduced acceptor

cis-1,2-dichloroethene + chloride + acceptor

Dehalococcoides mccartyi

-

-

746490

-

-

?

trichloroethene + reduced acceptor

cis-1,2-dichloroethene + chloride + acceptor

Sulfurospirillum multivorans

-

physiological electron donor is not known

349700

-

-

?

additional information

?

-

Dehalobacter restrictus

-

PCE reductase is the final enzyme of the perchloroethene respiratory chain that catalyzes the reductive cleavage of a carbon chlorine bond

349701

-

-

?

additional information

?

-

uncultured bacterium

D6RU53

using pull-down assays PceA1 interacts with DnaK (Hsp70)

714522

-

-

?

additional information

?

-

uncultured bacterium

D6RU55

using pull-down assays PceA1 interacts with DnaK (Hsp70)

714522

-

-

?