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1.21.99.3: thyroxine 5-deiodinase

This is an abbreviated version!
For detailed information about thyroxine 5-deiodinase, go to the full flat file.

Word Map on EC 1.21.99.3

Reaction

3,3',5'-triiodo-L-thyronine
+
Iodide
+
acceptor
+
H+
=
L-thyroxine
+
reduced acceptor

Synonyms

5'-deiodinase, D3, deiodinase, deiodinase 3, deiodinase, thyroxine 5-, deiodinase-3, diiodothyronine 5'-deiodinase, Dio, Dio3, Dio3a, Dio3b, EC 1.97.1.11, ID-3, iodothyronine 5-deiodinase, iodothyronine deiodinase type III, iodothyronine inner ring monodeiodinase, iodothyronine monodeiodinase, ITHD, T4-5'-deiodinase, T4-5-deiodinase, thyroxine 5-deiodinase, type 3 deiodinase, type 3 iodothyronine 5-deiodinase, type 3 iodothyronine deiodinase, type III deiodinase, type III iodothyronine deiodinase, type-3 deiodinase, zD3

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.99 With unknown physiological acceptors
                1.21.99.3 thyroxine 5-deiodinase

Sequence

Sequence on EC 1.21.99.3 - thyroxine 5-deiodinase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
IOD3_MOUSE
304
0
34111
Swiss-Prot
Mitochondrion (Reliability: 5)
IOD3_PIG
305
0
34042
Swiss-Prot
Mitochondrion (Reliability: 3)
IOD3_RAT
304
0
34096
Swiss-Prot
Mitochondrion (Reliability: 5)
IOD3_SHEEP
292
0
32772
Swiss-Prot
Secretory Pathway (Reliability: 5)
IOD3_SPAAU
267
1
30327
Swiss-Prot
Secretory Pathway (Reliability: 2)
IOD3_XENLA
271
1
30299
Swiss-Prot
Secretory Pathway (Reliability: 3)
IOD3_BOVIN
301
1
33888
Swiss-Prot
Mitochondrion (Reliability: 2)
IOD3_CHICK
258
0
28876
Swiss-Prot
Secretory Pathway (Reliability: 1)
IOD3_HUMAN
304
1
33947
Swiss-Prot
Mitochondrion (Reliability: 4)
IOD3_LITCT
269
1
30140
Swiss-Prot
Secretory Pathway (Reliability: 1)
A0A8M1P485_DANRE
264
1
30375
TrEMBL
Secretory Pathway (Reliability: 1)
A0A3G0ZGD9_DANRE
269
0
30042
TrEMBL
-
A9QW70_CHIPU
259
0
29604
TrEMBL
-
D2J363_9SAUR
286
0
31691
TrEMBL
-
D3Y4D3_DANRE
269
0
30022
TrEMBL
-
Q90Z53_XENLA
262
0
29632
TrEMBL
-
Q9I966_ORENI
267
0
30317
TrEMBL
-
IOD3_MOUSE
304
0
34111
Swiss-Prot
-