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1.21.98.3: anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase

This is an abbreviated version!
For detailed information about anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase, go to the full flat file.

Reaction

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
+
S-adenosyl-L-methionine
=
131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester
+
5'-deoxyadenosine
+
L-methionine

Synonyms

BChE, chlE, Cyan7425_4778, Cyan7822_3999, F_1025, Mg-protoporphyrin IX monomethyl ester cyclase, MPE cyclase, oxygen-independent Mg-protoporphyrin IX monomethyl ester cyclase

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.98 With other, known, physiological acceptors
                1.21.98.3 anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase

Systematic Name

Systematic Name on EC 1.21.98.3 - anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase

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SYSTEMATIC NAME
IUBMB Comments
magnesium-protoporphyrin-IX 13-monomethyl ester,S-adenosyl-L-methionine:H2O oxidoreductase (hydroxylating)
This radical AdoMet enzyme participates in the biosynthesis of chlorophyllide a in anaerobic bacteria, catalysing the formation of an isocyclic ring. Contains a [4Fe-4S] cluster and a cobalamin cofactor. The same transformation is achieved in aerobic organisms by the oxygen-dependent EC 1.14.13.81, magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase. Some facultative phototrophic bacteria, such as Rubrivivax gelatinosus, possess both enzymes.