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1.21.3.6: aureusidin synthase

This is an abbreviated version!
For detailed information about aureusidin synthase, go to the full flat file.

Word Map on EC 1.21.3.6

Reaction

2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside
+
1/2 O2
=
aureusidin 6-O-beta-D-glucoside
+
H2O

Synonyms

AmAS1, AS1, aureusidin synthase, aurone synthase, More, synthase, aureusidin

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.3 With oxygen as acceptor
                1.21.3.6 aureusidin synthase

Crystallization

Crystallization on EC 1.21.3.6 - aureusidin synthase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
homology modeling using grenache polyphenol oxidase and sweet potato catechol oxidase as templates. The structure is folded into 15alpha-helices and 5 beta-sheets, and mostly composed by loops. The core of the enzyme is formed by a four-helix-bundle, and the helical bundle accommodates the dinuclear copper center. The cysteine residues Cys11, Cys25, Cys26, and Cys88 are highly conserved, and form disulfide bridges