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1.20.4.1: arsenate reductase (glutathione/glutaredoxin)

This is an abbreviated version!
For detailed information about arsenate reductase (glutathione/glutaredoxin), go to the full flat file.

Word Map on EC 1.20.4.1

Reaction

arsenate
+
glutathione
+
glutaredoxin
=
arsenite
+
a glutaredoxin-glutathione disulfide
+
H2O

Synonyms

Acr2, Acr2p, ACR3-ArsC, All0195, AR, ARSA, ArsC, arsenate reductase, arsenate reductase (glutaredoxin), AsV reductase, EC 1.97.1.5, gene arsC proteins, glutaredoxin, glutathione:arsenate oxidoreductase, Grx, MXAN_0575, PcAcr2, proteins (specific proteins and subclasses), gene arsC, PvGRX5, reductase, arsenate, slr0946, SynArsC

ECTree

     1 Oxidoreductases
         1.20 Acting on phosphorus or arsenic in donors
             1.20.4 With disulfide as acceptor
                1.20.4.1 arsenate reductase (glutathione/glutaredoxin)

Natural Substrates Products

Natural Substrates Products on EC 1.20.4.1 - arsenate reductase (glutathione/glutaredoxin)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
arsenate + glutaredoxin
arsenite + glutaredoxin disulfide + H2O
show the reaction diagram
arsenate + reduced acceptor
arsenite + acceptor
show the reaction diagram
arsenate + reduced glutaredoxin
arsenite + oxidized glutaredoxin
show the reaction diagram
arsenate + reduced glutathione
arsenite + glutathione
show the reaction diagram
-
enzyme plays an important role in detoxification of arsenate
-
-
?
arsenite + acceptor
arsenate + reduced acceptor
show the reaction diagram
-
high activity
-
-
?