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1.20.1.1: phosphonate dehydrogenase

This is an abbreviated version!
For detailed information about phosphonate dehydrogenase, go to the full flat file.

Word Map on EC 1.20.1.1

Reaction

phosphonate
+
NAD+
+
H2O
=
phosphate
+
NADH
+
H+

Synonyms

NAD-dependent phosphite dehydrogenase, NAD:phosphite oxidoreductase, phosphite dehydrogenase, PTDH, PtxD

ECTree

     1 Oxidoreductases
         1.20 Acting on phosphorus or arsenic in donors
             1.20.1 With NAD+ or NADP+ as acceptor
                1.20.1.1 phosphonate dehydrogenase

Inhibitors

Inhibitors on EC 1.20.1.1 - phosphonate dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-Bromoethylamine
-
1 mM NAD+ protects against inactivation
arsenite
Cd2+
1 mM, no residual activity
Cu2+
1 mM, about 55% of initial activity
D,L-hydroxyisocaproate
-
D-2-hydroxy-4-methylvalerate
-
diethyl dicarbonate
-
-
Mn2+
1 mM, about 65% of initial activity
nitrate
sulfite
Zn2+
1 mM, about 35% of initial activity
additional information
-