1.2.1.B29: formate dehydrogenase (NADP+, ferredoxin)
This is an abbreviated version!
For detailed information about formate dehydrogenase (NADP+, ferredoxin), go to the full flat file.
Word Map on EC 1.2.1.B29
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1.2.1.B29
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thioredoxin
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goldi
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antiproliferative
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exergonic
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carbene
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fefe-hydrogenase
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n-heterocyclic
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naphthalimide
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selenocysteine
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selenols
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metallodrugs
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diselenide
- 1.2.1.B29
- thioredoxin
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goldi
-
antiproliferative
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exergonic
-
carbene
-
fefe-hydrogenase
-
n-heterocyclic
-
naphthalimide
- selenocysteine
-
selenols
-
metallodrugs
-
diselenide
Reaction
2 formate + + 2 oxidized ferredoxin [iron-sulfur] cluster = 2 CO2 + + + 2 reduced ferredoxin [iron-sulfur] cluster
Synonyms
electron-bifurcating [FeFe]-hydrogenase
ECTree
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General Information
General Information on EC 1.2.1.B29 - formate dehydrogenase (NADP+, ferredoxin)
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physiological function
S5Z061; S5YUC5
the enzyme complex catalyzes both the reversible coupled reduction of ferredoxin and NADP+ with H2 or formate and the reversible formation of H2 and CO2 from formate. The complex has two functions in vivo, namely, to normally catalyze CO2 reduction to formate with NADPH and reduced ferredoxin in the Wood-Ljungdahl pathway and to catalyze H2 formation from NADPH and reduced ferredoxin when these redox mediators get too reduced during unbalanced growth on CO
physiological function
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the enzyme complex catalyzes both the reversible coupled reduction of ferredoxin and NADP+ with H2 or formate and the reversible formation of H2 and CO2 from formate. The complex has two functions in vivo, namely, to normally catalyze CO2 reduction to formate with NADPH and reduced ferredoxin in the Wood-Ljungdahl pathway and to catalyze H2 formation from NADPH and reduced ferredoxin when these redox mediators get too reduced during unbalanced growth on CO
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