1.2.1.B23: 4,4'-diaponeurosporen-aldehyde dehydrogenase
This is an abbreviated version!
For detailed information about 4,4'-diaponeurosporen-aldehyde dehydrogenase, go to the full flat file.
Reaction
Synonyms
ALDH, NWMN_2026
ECTree
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General Information
General Information on EC 1.2.1.B23 - 4,4'-diaponeurosporen-aldehyde dehydrogenase
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physiological function
final enzyme in the biosynthetic pathway for staphyloxanthin, a C30 carotenoid biosynthesized by Staphylococcus aureus. Deletion of the gene abolishes staphyloxanthin biosynthesis and causes accumulation of 4,4'-diaponeurosporen-4-al. When the complete staphyloxanthin biosynthetic pathway is expressed using an artificial synthetic operon in Escherichia coli, staphyloxanthin-like compounds, which contain altered fatty acid acyl chains, and novel carotenoid compounds aere produced, indicating functional expression and coordination of the six staphyloxanthin pathway enzymes