1.2.1.88: L-glutamate gamma-semialdehyde dehydrogenase
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For detailed information about L-glutamate gamma-semialdehyde dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.88
Reaction
Synonyms
1-pyrroline dehydrogenase, aldehyde dehydrogenase 12, ALDH12, Aldh4a1, dehydrogenase, 1-pyrroline-5-carboxylate, DELTA1-pyrroline-5-carboxylate dehydrogenase, delta1-pyrroline-5-carboxylate synthetase, DR_0813, EC 1.5.1.12, GSAL dehydrogenase, GSALDH, l-glutamate-gamma-semialdehyde dehydrogenase, L-pyrroline-5-carboxylate-NAD+ oxidoreductase, LRRP Ba1-651, NAD+-dependent glutamate gamma-semialdehyde dehydrogenase, OsALDH12, OsALDH18-2, P5C dehydrogenase, P5C synthase, P5C-DH, P5CD, P5CDH, P5CDH1, P5CS, PDH, PpALDH12, proline/P5C dehydrogenase, Put2, PutA, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylate synthase, pyrroline-5-carboxylic acid dehydrogenase, Tc00.1047053510943.50, YcgN, ZmALDH12
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Disease on EC 1.2.1.88 - L-glutamate gamma-semialdehyde dehydrogenase
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Atherosclerosis
ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies.
Cataract
Investigation of eight candidate genes on chromosome 1p36 for autosomal dominant total congenital cataract.
Epilepsy
Metabolic epilepsy in hyperprolinemia type II due to a novel nonsense ALDH4A1 gene variant.
Fascioliasis
Proline in fascioliasis: III. Activities of pyrroline-5-carboxylic acid reductase and pyrroline-5-carboxylic acid dehydrogenase in Fasciola.
Granuloma
Proline trapping in granulomas, the site of collagen biosynthesis in murine schistosomiasis.
Hypersensitivity
The role of [Delta]1-pyrroline-5-carboxylate dehydrogenase in proline degradation.
Infections
P5CDH affects the pathways contributing to Pro synthesis after ProDH activation by biotic and abiotic stress conditions.
Infections
Proteomic comparison of Mycobacterium avium subspecies paratuberculosis grown in vitro and isolated from clinical cases of ovine paratuberculosis.
Infections
Reactive oxygen species homeostasis and virulence of the fungal pathogen Cryptococcus neoformans requires an intact proline catabolism pathway.
l-glutamate gamma-semialdehyde dehydrogenase deficiency
Crystal Structure of Thermus thermophilus Delta(1)-Pyrroline-5-carboxylate Dehydrogenase.
Metabolic Diseases
Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease.
Metabolic Syndrome
In Vivo Exposures to Particulate Matter Collected from Saudi Arabia or Nickel Chloride Display Similar Dysregulation of Metabolic Syndrome Genes.
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