1.2.1.72: erythrose-4-phosphate dehydrogenase

This is an abbreviated version!
For detailed information about erythrose-4-phosphate dehydrogenase, go to the full flat file.

Reaction

Synonyms

E4P dehydrogenase, E4PD, E4PDH, epd, Epd dehydrogenase, erythrose 4-phosphate dehydrogenase, gap2, GapB, gapB-encoded dehydrogenase, GapB-encoded protein

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.72 erythrose-4-phosphate dehydrogenase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
2870	AA Sequence
1	Application
1	CAS Registry Number
1	Cloned(Commentary)
3	Cofactor
14	KM Value [mM]
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
7	Organism
5	Pathway
24	PDB ID
1	pH Optimum
8	Protein Variants
2	Purification (Commentary)
1	Reaction
3	Reaction Type
7	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
12	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
14	Turnover Number [1/s]

Engineering

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Engineering on EC 1.2.1.72 - erythrose-4-phosphate dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Protein Variants Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

C149A

Escherichia coli

-

no significant phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity

662097

C149G

Escherichia coli

-

no significant phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity

662097

C149V

Escherichia coli

-

no significant phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity

662097

C311A

Escherichia coli

-

mutation does not drastically change the phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity. 5.7fold decrease in turnover number for the activity with D-erythrose 4-phosphate and NAD+

662097

C311Y

Escherichia coli

-

mutation does not drastically change the phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity. 33.3fold decrease in turnover number for the activity with D-erythrose 4-phosphate and NAD+

662097

E32D

Escherichia coli

-

mutation does not drastically change the phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity. 2.7fold decrease in turnover number for the activity with D-erythrose 4-phosphate and NAD+

662097

H176N

Escherichia coli

-

turnover number of phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity is decreased by the factor 40. 95.2fold decrease in turnover number for the activity with D-erythrose 4-phosphate and NAD+

662097

M179T

Escherichia coli

-

mutation does not drastically change the phosphorylating glyceraldehyde-3-phosphate dehydrogenase activity. 5fold decrease in turnover number for the activity with D-erythrose 4-phosphate and NAD+

662097