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1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase

This is an abbreviated version!
For detailed information about 4-trimethylammoniobutyraldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.47

Reaction

4-Trimethylammoniobutanal
+
NAD+
+
H2O
=
4-Trimethylammoniobutanoate
+
NADH
+ 2 H+

Synonyms

4-N-trimethylaminobutyraldehyde dehydrogenase, 4-N-trimethylaminobutyraldehyde dehydrogenase II, 4-trimethylaminobutyraldehyde dehydrogenase, 4-trimethylammoniobutyraldehyde dehydrogenase, aldehyde dehydrogenase 9A1, Aldh9a1, carnitine biosynthesis enzyme, dehydrogenase, trimethylaminobutyraldehyde, gamma-trimethylaminobutyraldehyde dehydrogenase, TMABA dehydrogenase, TMABA-DH, TMABADH, TMABAL dehydrogenase, TMABaldehyde-DH II, TMABALDH

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase

Temperature Stability

Temperature Stability on EC 1.2.1.47 - 4-trimethylammoniobutyraldehyde dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
25 - 30
the enzyme is stable up to 25°C while incubation for 30 min at 30°C and above leads to rapid inactivation
30
-
the enzyme is rapidly inactivated at temperatures above 35°C
4
-
0.1% 2-mercaptoethanol, 20% glycerol, fairly stable, but storage for several weeks results in loss of most of the activity