1.2.1.46: formaldehyde dehydrogenase

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For detailed information about formaldehyde dehydrogenase, go to the full flat file.

Reaction

Synonyms

ADH3, dehydrogenase, formaldehyde, DL-FDH, dlFalDH, dye-linked formaldehyde dehydrogenase, FADH, FALDH, FdDH, FDH, FDH1, fdhA, FldDH, Fldh1, formaldehyde dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, glutathione-dependent formaldehyde dehydrogenase/alcohol dehydrogenase, glutathione-independent FDH, glutathione-independent formaldehyde dehydrogenase, GSH-FDH/ADH, NAD+- and glutathione-dependent formaldehyde dehydrogenase, NAD+- and glutathione-independent formaldehyde dehydrogenase, NAD+- and glutathione_dependent formaldehyde dehydrogenase, NAD+-dependent formaldehyde dehydrogenase, NAD-dependent formaldehyde dehydrogenase, NAD-linked formaldehyde dehydrogenase

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.46 formaldehyde dehydrogenase

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Results	in table
6	Activating Compound
1863	AA Sequence
14	Application
1	CAS Registry Number
9	Cloned(Commentary)
40	Cofactor
4	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
8	General Information
6	General Stability
39	Inhibitors
6	kcat/KM [mM/s]
13	Ki Value [mM]
38	KM Value [mM]
1	Localization
18	Metals/Ions
14	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
115	Organism
6	Pathway
2	PDB ID
14	pH Optimum
3	pH Range
4	pH Stability
4	Protein Variants
16	Purification (Commentary)
4	Reaction
6	Reaction Type
52	Reference
9	Source Tissue
15	Specific Activity [micromol/min/mg]
6	Storage Stability
95	Substrates and Products (Substrate)
23	Subunits
63	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Temperature Stability [°C]
5	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 1.2.1.46 - formaldehyde dehydrogenase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

30 - 65

Ogataea angusta

-

at 65°C, the enzyme retains about 60% of its highest activity (assay time of ca. 5 min), which is equal to the level of FdDH activity at 30°C

686818

40

Pseudomonas putida

-

30 min, pH 7.5, stable

288248

45

Arthrobacter sp.

-

stable for 6 min

288245

55

Pseudomonas putida

-

pH 7.5, 30 min, 50% loss of activity

288248