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1.2.1.46: formaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about formaldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.46

Reaction

formaldehyde
+
NAD+
 +
H2O
=
formate
 +
NADH
 +
H+

Synonyms

ADH3, dehydrogenase, formaldehyde, DL-FDH, dlFalDH, dye-linked formaldehyde dehydrogenase, FADH, FALDH, FdDH, FDH, FDH1, fdhA, FldDH, Fldh1, formaldehyde dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, glutathione-dependent formaldehyde dehydrogenase/alcohol dehydrogenase, glutathione-independent FDH, glutathione-independent formaldehyde dehydrogenase, GSH-FDH/ADH, NAD+- and glutathione-dependent formaldehyde dehydrogenase, NAD+- and glutathione-independent formaldehyde dehydrogenase, NAD+- and glutathione_dependent formaldehyde dehydrogenase, NAD+-dependent formaldehyde dehydrogenase, NAD-dependent formaldehyde dehydrogenase, NAD-linked formaldehyde dehydrogenase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.46 formaldehyde dehydrogenase

Substrates Products

Substrates Products on EC 1.2.1.46 - formaldehyde dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetaldehyde + NAD+ + H2O
acetate + NADH + H+
show the reaction diagram
aryl alcohol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
benzyl alcohol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
formaldehyde + H2O + NAD+
formate + NADH + H+
show the reaction diagram
formaldehyde + NAD+ + H2O
formate + NADH
show the reaction diagram
formaldehyde + NAD+ + H2O
formate + NADH + 2 H+
show the reaction diagram
formaldehyde + NAD+ + H2O
formate + NADH + H+
show the reaction diagram
formate + NADH + 2 H+
formaldehyde + NAD+ + H2O
show the reaction diagram
-
-
-
-
r
formate + reduced methyl viologen + 2 H+
formaldehyde + oxidized methyl viologen + H2O
show the reaction diagram
-
single-electron reduced methyl viologen activates the enzyme activity for formate reduction to formaldehyde
-
-
?
glyoxal + NAD+ + H2O
glyoxylate + NADH
show the reaction diagram
isobutanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
isobutyraldehyde + NAD+ + H2O
isobutyrate + NADH + H+
show the reaction diagram
-
-
-
-
r
isopentanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
n-butanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
n-hexanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
n-pentanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
n-propanol + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+ + H2O
propionate + NADH
show the reaction diagram
propionaldehyde + NAD+ + H2O
propionate + NADH + H+
show the reaction diagram
-
95% activity compared to propionaldehyde
-
-
?
pyruvaldehyde + NAD+ + H2O
pyruvate + NADH
show the reaction diagram
S-hydroxymethylglutathione + NAD+ + H2O
S-formylglutathione + NADH + H+
show the reaction diagram
-
-
-
-
?
S-nitrosoglutathione + NADH + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-