1.2.1.42: hexadecanal dehydrogenase (acylating)

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For detailed information about hexadecanal dehydrogenase (acylating), go to the full flat file.

Reaction

Synonyms

ACIAD3383, Acr1, AtFAR2, CoA-acylating aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, dehydrogenase, hexadecanal (acylating), FACoAR, FAR, FAR1, FAR2, FAR6, fatty acid reductase, fatty acyl-CoA reductase, MS2, PduP

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.42 hexadecanal dehydrogenase (acylating)

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Results	in table
8	Activating Compound
12	AA Sequence
1	CAS Registry Number
14	Cloned(Commentary)
16	Cofactor
3	General Information
2	Inhibitors
2	kcat/KM [mM/s]
13	KM Value [mM]
7	Localization
9	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
21	Organism
1	Oxidation Stability
8	pH Optimum
3	pH Range
6	Protein Variants
7	Purification (Commentary)
2	Reaction
3	Reaction Type
21	Reference
6	Source Tissue
13	Specific Activity [micromol/min/mg]
58	Substrates and Products (Substrate)
8	Subunits
31	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
2	Turnover Number [1/s]

Engineering

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Engineering on EC 1.2.1.42 - hexadecanal dehydrogenase (acylating)

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

C171S

Photobacterium leiognathi

-

99% of wild-type activity

288212

C279S

Photobacterium leiognathi

-

79% of wild -type activity

288212

C286S

Photobacterium leiognathi

-

2% of wild-type activity

288212

C171S

Photobacterium phosphoreum

-

77% of wild-type activity

288212

C279S

Photobacterium phosphoreum

-

90% of wild-type activity

288212

C286S

Photobacterium phosphoreum

-

9% of wild-type activity

288212