raldh4 mRNA is present in developing intestine regions at 2 dpf embryos. Its expression level becomes very high in embryos from 3 dpf to 5 dpf. In 5 dpf embryos raldh4 is expressed in the epithelium of intestine. At 7 dpf, raldh4 mRNA is only weakly expressed in the epithelium of intestinal bulb
at 9.5 and 10.5 days of embryonic development the enzyme activity is restricted to tissues of the embryonic trunk and absent in extracts from cranial tissues
raldh3 mRNA is first expressed in the developing eye region of zebrafish embryos at 10-somite stage. At 24 hpf (hours post fertilization), raldh3 mRNA is expressed in the ventral retina of eye. At 36 hpf, the mRNA is also expressed in otic vesicle in addition to ventral retina, and it maintains its expression pattern till 2 dpf (days post fertilization). At 3 dpf, raldh3 mRNA becomes very weak in ventral retina but is present in otic vesicle at a high level. At 5 dpf and 7 dpf, raldh3 is no longer expressed in eyes but is expressed in otic vesicles at a very low level
expression of RALDH2 is located in Rathke's pouch at embryonic day 12.5 and subsequently in the developing anterior pituitary gland. Pituitary RALDH2 mRNA levels are high at E17.5 and decrease markedly after birth
expression of RALDH3 is located in Rathke's pouch at embryonic day 12.5 and subsequently in the developing anterior pituitary gland. Pituitary RALDH3 mRNA levels are high at E17.5 and decrease markedly after birth
high level of RALDH1 mRNA but not of RALDH2 mRNA or RALDH3 mRNA in anterior pituitary gland of adult rats. RALDH1 mRNA is barely expressed in the embryonic pituitary glands. After birth, RALDH1 mRNA is markedly expressed and gradually increased throughout growth
ALDH1A1 is highly expressed in lung carcinoma cell line A549 and EKVX, as well as in the large cell carcinoma cell line H460. Isozyme ALDH3A1 (EC 1.2.1.5) shows a similar expression pattern like ALDH1A1. Other members of the aldehyde dehydrogenase family are not expressed in the lung cancer cell lines examined
present in prolactin (PRL)-producing cells, FS-cells and marginal layer cells. RALDH1 mRNA is not expressed in cells that produce adrenocorticotrophic hormone, GH, thyroid-stimulating hormone, or luteinizing hormone