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1.2.1.31: L-aminoadipate-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about L-aminoadipate-semialdehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.31

Reaction

(S)-2-amino-6-oxohexanoate
+
NAD(P)+
+
H2O
=
L-2-aminoadipate
+
NAD(P)H
+
H+

Synonyms

2-aminoadipate semialdehyde dehydrogenase, 2-aminoadipic 6-semialdehyde dehydrogenase, 2-aminoadipic semialdehyde dehydrogenase, AAR, AASADH, adipic 6-semialdehyde dehydrogenase, aldehyde dehydrogenase 7A1, Aldh7a1, alpha-AAR, alpha-AASA dehydrogenase, alpha-aminoadipate reductase Lys1p, alpha-aminoadipate semialdehyde dehydrogenase, alpha-aminoadipate-semialdehyde dehydrogenase, alpha-aminoadipic acid-delta-semialdehyde dehydrogenase, alpha-aminoadipic semialdehyde dehydrogenase, Alpha-AR, antiquitin, dehydrogenase, aminoadipate semialdehyde, human U26, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase, L-aminoadipate-semialdehyde dehydrogenase, Lys1p, Nalpha-Z-L-AASA dehydrogenase, U26

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.2.1.31 - L-aminoadipate-semialdehyde dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(S)-2-amino-6-oxohexanoate + NAD+ + H2O
L-2-aminoadipate + NADH + H+
show the reaction diagram
-
-
-
?
(S)-2-amino-6-oxohexanoate + NADP+ + H2O
L-2-aminoadipate + NADPH + H+
show the reaction diagram
-
-
-
?
alpha-aminoadipate semialdehyde + NAD(P)+ + H2O
L-2-aminoadipate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
L-2-aminoadipate + NADPH + H+
L-2-aminoadipate 6-semialdehyde + NADP+ + H2O
show the reaction diagram
L-2-aminoadipate 6-semialdehyde + NAD(P)+ + H2O
L-2-aminoadipate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
L-2-aminoadipate-semialdehyde + NAD+
L-2-aminoadipate + NADH
show the reaction diagram
L-alpha-aminoadipate + NAD(P)H
L-alpha-aminoadipate-semialdehyde + NAD(P)+ + H2O
show the reaction diagram
additional information
?
-
-
the enzyme catalyzes both the activation of alpha-aminoadipic acid and its reduction to semialdehyde
-
-
?