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1.2.1.26: 2,5-dioxovalerate dehydrogenase

This is an abbreviated version!
For detailed information about 2,5-dioxovalerate dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.26

Reaction

2,5-dioxopentanoate
+
NADP+
+
H2O
=
2-oxoglutarate
+
NADPH
+
H+

Synonyms

2-oxoglutarate semialdehyde dehydrogenase, AbKGSADH, aldehyde dehydrogenase, ALDH, alpha-ketoglutarate semialdehyde dehydrogenase, alpha-ketoglutarate-semialdehyde dehydrogenase, alpha-ketoglutaric semialdehyde dehydrogenase, alpha-KGSA dehydrogenase, alphaKGSA dehydrogenase, alphaKGSADH, araE, DopDH, KGSADH, KGSADH-I, KGSADH-II, KGSADH-III, More, SSO3117, ycbD protein

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.26 2,5-dioxovalerate dehydrogenase

Substrates Products

Substrates Products on EC 1.2.1.26 - 2,5-dioxovalerate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,5-dioxopentanoate + NAD(P)+ + H2O
2-oxoglutarate + NAD(P)H
show the reaction diagram
2,5-dioxopentanoate + NAD+ + H2O
2-oxoglutarate + NADH + H+
show the reaction diagram
2,5-dioxopentanoate + NADP+ + H2O
2-oxoglutarate + NADPH + 2 H+
show the reaction diagram
2-oxoglutaric semialdehyde + NAD(P)+ + H2O
2-oxoglutarate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
2-oxoglutaric semialdehyde + NAD+ + H2O
2-oxoglutarate + NADH + H+
show the reaction diagram
-
-
-
?
3-hydroxypropionaldehyde + NAD+
3-hydroxypropionate + NADH + H+
show the reaction diagram
3-hydroxypropionaldehyde + NADP+
3-hydroxypropionate + NADPH + H+
show the reaction diagram
very low activity
-
-
?
acetaldehyde + NAD(P)+ + H2O
acetate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
alpha-ketoglutaric semialdehyde + NAD(P)+ + H2O
alpha-ketoglutarate + NAD(P)H + H+
show the reaction diagram
alpha-ketoglutaric semialdehyde + NADP+ + H2O
alpha-ketoglutarate + NADPH + H+
show the reaction diagram
-
-
-
?
butyraldehyde + NAD(P)+ + H2O
n-butanoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
butyraldehyde + NAD+
butanoate + NADH + H+
show the reaction diagram
-
-
-
?
DL-glyceraldehyde + NADP+ + H2O
glycerate + NADPH + H+
show the reaction diagram
glutaraldehyde + NAD(P)+ + H2O
glutarate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
glutaric semialdehyde + NADP+ + H2O
glutarate + NADPH
show the reaction diagram
-
-
-
?
glycolaldehyde + NADP+ + H2O
glycolate + NADPH + H+
show the reaction diagram
heptaldehyde + NAD(P)+ + H2O
n-heptanoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
hexaldehyde + NAD+
hexanoate + NADH + H+
show the reaction diagram
-
-
-
?
hexylaldehyde + NAD(P)+ + H2O
n-hexanoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
octylaldehyde + NAD(P)+ + H2O
n-octanoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
propanal + NAD(P)+ + H2O
propionate + NAD(P)H + H+
show the reaction diagram
-
-
-
?
propionaldehyde + NAD(P)+ + H2O
propionate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
propionaldehyde + NAD+
propionate + NADH + H+
show the reaction diagram
-
-
-
?
succinate semialdehyde + NAD(P)+ + H2O
? + NAD(P)H + H+
show the reaction diagram
-
-
-
?
succinate semialdehyde + NAD+ + H2O
succinate + NADH + H+
show the reaction diagram
valeraldehyde + NAD(P)+ + H2O
n-pentanoate + NAD(P)H + H+
show the reaction diagram
-
-
-
-
?
valeraldehyde + NAD+
valerate + NADH + H+
show the reaction diagram
-
-
-
?
additional information
?
-