Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.2.1.26: 2,5-dioxovalerate dehydrogenase

This is an abbreviated version!
For detailed information about 2,5-dioxovalerate dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.26

Reaction

2,5-dioxopentanoate
+
NADP+
+
H2O
=
2-oxoglutarate
+
NADPH
+
H+

Synonyms

2-oxoglutarate semialdehyde dehydrogenase, AbKGSADH, aldehyde dehydrogenase, ALDH, alpha-ketoglutarate semialdehyde dehydrogenase, alpha-ketoglutarate-semialdehyde dehydrogenase, alpha-ketoglutaric semialdehyde dehydrogenase, alpha-KGSA dehydrogenase, alphaKGSA dehydrogenase, alphaKGSADH, araE, DopDH, KGSADH, KGSADH-I, KGSADH-II, KGSADH-III, More, SSO3117, ycbD protein

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.26 2,5-dioxovalerate dehydrogenase

Cloned

Cloned on EC 1.2.1.26 - 2,5-dioxovalerate dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as His6-tagged ycbD protein
-
expression in Escherichia coli
expression in Escherichia coli BL21 (DE3)
gene araE, sequence comparisons of 3-hydroxypropionate producing ALDHs, recombinant expression of His6-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)-T1
KGSADH-II overexpressed as His6-tagged protein in Escherichia coli DH5alpha
KGSADH-III overexpressed as His6-tagged protein in Escherichia coli DH5alpha
recombinant expression of N-terminally His6-tagged wild-type and mutant KGSADH enzymes in Escherichia coli strain DH10beta