1.2.1.23: 2-oxoaldehyde dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about 2-oxoaldehyde dehydrogenase (NAD+), go to the full flat file.

Word Map on EC 1.2.1.23

1.2.1.23

glyoxalase

lactate

albicans

glutathione-depleted

nadh-linked

Reaction

Synonyms

2-ketoaldehyde dehydrogenase, ADH1, alpha-ketoaldehyde dehydrogenase, methylglyoxal dehydrogenase, MGD, NAD+-linked alcohol dehydrogenase 1, NAD+-linked methylglyoxal dehydrogenase, NAD-dependent alpha-ketoaldehyde dehydrogenase, NAD-linked alpha-ketoaldehyde dehydrogenase

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)

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Results	in table
18	Activating Compound
1	AA Sequence
3	CAS Registry Number
2	Cloned(Commentary)
22	Cofactor
1	Expression
2	General Information
38	Inhibitors
2	kcat/KM [mM/s]
38	KM Value [mM]
3	Metals/Ions
6	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
14	Organism
3	Pathway
4	pH Optimum
4	pH Range
1	Protein Variants
7	Purification (Commentary)
1	Reaction
3	Reaction Type
14	Reference
15	Source Tissue
9	Specific Activity [micromol/min/mg]
2	Storage Stability
40	Substrates and Products (Substrate)
4	Subunits
10	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.2.1.23 - 2-oxoaldehyde dehydrogenase (NAD+)

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2-amino-2-methylpropan-1,3-diol

Ovis aries

activation of aldehyde oxidation

288143

2-amino-2-methylpropan-1-ol

Ovis aries

activation of aldehyde oxidation

288143

2-Aminobutan-1-ol

Ovis aries

activation of aldehyde oxidation

288143

2-aminopropane

Ovis aries

activation of aldehyde oxidation

288143

2-aminopropane-1,3-diol

Ovis aries

activation of aldehyde oxidation

288143

beta-mercaptoethanol

Capra hircus

restores the activity after inactivation with p-chloromercuribenzoate

288140

dihydroxyacetone phosphate

stimulation

dithiothreitol

activation

fructose 1,6-bisphosphate

2 entries

glutathione

Pseudomonas putida

activation

288138

Glycerate 3-phosphate

Pseudomonas putida

slightly activation

288138

L-2-Aminopropan-1-ol

Ovis aries

activation of aldehyde oxidation

L-cysteine

activation

phosphate

activation

Tris

activation of aldehyde oxidation

288143