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1.2.1.21: glycolaldehyde dehydrogenase

This is an abbreviated version!
For detailed information about glycolaldehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.21

Reaction

glycolaldehyde
+
NAD+
+
H2O
=
glycolate
+
NADH
+
H+

Synonyms

ALDH, ALDH3I1, ALDH7B4, dehydrogenase, glycol aldehyde

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.21 glycolaldehyde dehydrogenase

Substrates Products

Substrates Products on EC 1.2.1.21 - glycolaldehyde dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetaldehyde + NAD+ + H2O
acetate + NADH + H+
show the reaction diagram
benzaldehyde + NAD+ + H2O
benzoate + NADH + H+
show the reaction diagram
betaine + NADH
betaine aldehyde + NAD+ + H2O
show the reaction diagram
-
isozyme A 139% of activity with glycolate, isozyme B, 76%
glucono-delta-lactone is not used as substrate
?
DL-glyceraldehyde + NAD+ + H2O
2,3-dihydroxypropanoic acid + NADH + H+
show the reaction diagram
-
-
-
?
formate + NADH
methanal + NAD+
show the reaction diagram
-
isozyme A, 163% of activity with glycolate
-
?
glycolaldehyde + NAD+ + H2O
glycolate + NADH
show the reaction diagram
glycolaldehyde + NAD+ + H2O
glycolate + NADH + 2 H+
show the reaction diagram
-
-
-
?
glycolaldehyde + NADP+ + H2O
glycolate + NADPH + H+
show the reaction diagram
glyoxylate + NADH
glyoxal + NAD+
show the reaction diagram
-
isozyme A, 417% of activity with glycolate, isozyme B 714%, isozyme C 150%
-
?
hydroxypyruvate + NAD+ + H2O
?
show the reaction diagram
-
-
-
-
?
malonate + NADH
malonic semialdehyde + NAD+ + H2O
show the reaction diagram
-
isozyme A, 83% of activity with glycolate
-
-
?
oxalate + NADH
glyoxylate + NAD+
show the reaction diagram
propionaldehyde + NAD+ + H2O
propionate + NADH
show the reaction diagram
succinate + NADH
succinic semialdehyde + NAD+ + H2O
show the reaction diagram