1.19.1.1: flavodoxin-NADP+ reductase

This is an abbreviated version!
For detailed information about flavodoxin-NADP+ reductase, go to the full flat file.

Reaction

Synonyms

Bc_0385, ferredoxin (flavodoxin):NADP+ oxidoreductase, ferredoxin/flavodoxin-NADP(H) oxidoreductase, FLDR, FNR, FPR, PETH, YumC

ECTree

     1 Oxidoreductases

         1.19 Acting on reduced flavodoxin as donor

             1.19.1 With NAD+ or NADP+ as acceptor

                1.19.1.1 flavodoxin-NADP+ reductase

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Results	in table
1	Activating Compound
1691	AA Sequence
7	Cloned(Commentary)
6	Cofactor
6	Crystallization (Commentary)
3	General Information
2	General Stability
16	kcat/KM [mM/s]
29	KM Value [mM]
1	Localization
6	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
216	Organism
2	PDB ID
2	pI Value
24	Protein Variants
2	Purification (Commentary)
1	Reaction
28	Reference
1	Source Tissue
35	Substrates and Products (Substrate)
11	Subunits
16	Synonyms
1	Systematic Name
3	Temperature Stability [°C]
27	Turnover Number [1/s]

Natural Substrates Products

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of the Enzyme Summary Page.

Natural Substrates Products on EC 1.19.1.1 - flavodoxin-NADP+ reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

FMNH2 + NADP+

FMN + NADPH + H+

Escherichia coli

P28861

-

657646

-

-

?

reduced flavodoxin I + NADP+

oxidized flavodoxin I + NADPH + H+

Escherichia coli

P28861

-

657646

-

-

?

reduced flavodoxin II + NADP+

oxidized flavodoxin II + NADPH + H+

Escherichia coli

P28861

-

657646

-

-

?

additional information

?

-

Escherichia coli

P28861

the enzyme reduces flavodoxin I, flavodoxin II and ferredoxin, ferredoxin being the kinetically and thermodynamically preferred partner, i.e. reaction of EC 1.18.2.1. Flavodoxin I and flavodoxin II behave similarly with respect to FNR, with affinities about 4- to 7fold weaker and reduction rates that are 10- to 100fold slower than those for ferredoxin. Flavodoxin I and flavodoxin II can obtain electrons from reduced Fd at rates that are comparable to those obtained with reduced FNR

657646

-

-

?