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1.17.4.2: ribonucleoside-triphosphate reductase (thioredoxin)

This is an abbreviated version!
For detailed information about ribonucleoside-triphosphate reductase (thioredoxin), go to the full flat file.

Word Map on EC 1.17.4.2

Reaction

2'-deoxyribonucleoside 5'-triphosphate
+
thioredoxin disulfide
+
H2O
=
ribonucleoside 5'-triphosphate
+
thioredoxin

Synonyms

2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase, adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, class Ib ribonucleotide reductase, class Ib RNR, class II ribonucleotide reductase, class II RNR, class III ribonucleotide reductase, class III RNR, More, nrdD, nucleoside triphosphate reductase, ribonucleoside triphosphate reductase, ribonucleotide diphosphate reductase, ribonucleotide reductase, RNR, RNR class Ia, RNR2, RTPR

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.4 With a disulfide as acceptor
                1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin)

Activating Compound

Activating Compound on EC 1.17.4.2 - ribonucleoside-triphosphate reductase (thioredoxin)

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2',5'-dideoxyadenosylcobalamin anilide
-
-
2-mercaptoethanol
-
-
5'-deoxy-5'-adenosylcobalamin
-
-
5'-deoxyadenosylcobalamin
5'-deoxyadenosylcobalamin anilide
-
-
5'-deoxyuridylcobalamin
-
-
cyanocobalamin
-
-
cyanocobalamin anilide
-
-
cyanocobalamin dibasic acid
-
-
cyanocobalamin ethylamide
-
-
-
cyanocobalamin monobasic acid
-
-
ethyl cobalamin
-
-
hydroxocobalamin
-
-
hydroxocobalamin methylamide
-
-
methyl cobalamin
-
-
NADPH
-
stimulates reductase activity in crude extracts