1.17.2.1: nicotinate dehydrogenase (cytochrome)

This is an abbreviated version!
For detailed information about nicotinate dehydrogenase (cytochrome), go to the full flat file.

Reaction

Synonyms

ndhSL, NicA, NicB

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.2 With a cytochrome as acceptor

                1.17.2.1 nicotinate dehydrogenase (cytochrome)

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Results	in table
591	AA Sequence
1	Cloned(Commentary)
5	Cofactor
1	Metals/Ions
6	Molecular Weight [Da]
46	Organism
4	Pathway
1	pH Optimum
1	Reaction
6	Reference
9	Substrates and Products (Substrate)
11	Subunits
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.17.2.1 - nicotinate dehydrogenase (cytochrome)

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SYSTEMATIC NAME

IUBMB Comments

nicotinate:cytochrome 6-oxidoreductase (hydroxylating)

This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases, but differs from most other members of this family. While most members contain an FAD cofactor, the large subunit of this enzyme contains three c-type cytochromes, enabling it to interact with the electron transfer chain, probably by delivering the electrons to a cytochrome oxidase. The small subunit contains a typical molybdopterin cytosine dinucleotide(MCD) cofactor and two [2Fe-2S] clusters [1].