1.17.1.8: 4-hydroxy-tetrahydrodipicolinate reductase

This is an abbreviated version!
For detailed information about 4-hydroxy-tetrahydrodipicolinate reductase, go to the full flat file.

Word Map on EC 1.17.1.8

1.17.1.8

diaminopimelate

glutamicum

meso-diaminopimelate

aspartokinase

imine

dhdps

2,6-pyridinedicarboxylate

medicine

alpha,beta-unsaturated

2'-phosphate

s-2-aminoethyl-l-cysteine

aspartate-semialdehyde

drug development

agriculture

Reaction

(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

Synonyms

AbDHDPR, CRR1, DapB, DHDP reductase, DHDPR, DHPR, dihydrodipicolinate reductase, dihydrodipicolinate reductase-like protein, dihydrodipicolinic acid reductase, EC 1.3.1.26, MRSA-DHDPR, reductase, dihydrodipicolinate

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.1 With NAD⁺ or NADP⁺ as acceptor

1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase

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Results	in table
8	Activating Compound
36207	AA Sequence
6	Application
1	CAS Registry Number
26	Cloned(Commentary)
65	Cofactor
16	Crystallization (Commentary)
18	General Information
61	Inhibitors
15	Ki Value [mM]
60	KM Value [mM]
3	Localization
31	Molecular Weight [Da]
39	Natural Substrates/ Products (Substrates)
76	Organism
11	Pathway
56	PDB ID
13	pH Optimum
3	pH Range
7	Protein Variants
24	Purification (Commentary)
13	Reaction
3	Reaction Type
59	Reference
3	Source Tissue
16	Specific Activity [micromol/min/mg]
2	Storage Stability
100	Substrates and Products (Substrate)
38	Subunits
71	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
17	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.17.1.8 - 4-hydroxy-tetrahydrodipicolinate reductase

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0.01 - 0.079

Brevibacillus brevis

depending on growth phase, similar course but lower activity for asporogenic mutant BH 7

390610

0.029

Lysinibacillus sphaericus

during stationary phase

390194

0.04

Lysinibacillus sphaericus

during late exponential phase

390194

1.153

Lactiplantibacillus plantarum

pH 7.5, 30°C, recombinant enzyme

670165

10.1

Staphylococcus aureus

purified recombinant enzyme, pH not specified in the publication, temperature not specified in the publication

135

purified enzyme

15.4

300

purified enzyme

398

purified enzyme

4.67

56.4

purified enzyme

6.86

additional information

4 entries