1.17.1.5: nicotinate dehydrogenase

This is an abbreviated version!
For detailed information about nicotinate dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, nicotinate, EC 1.5.1.13, NA hydroxylase, NAH, NahAB1B2, NDH, NdhL, NdhM, NdhS, nicotinate dehydrogenase, nicotinic acid hydroxylase, three-component NA hydroxylase, three-component nicotinic acid hydroxylase

ECTree

     1 Oxidoreductases

         1.17 Acting on CH or CH₂ groups

             1.17.1 With NAD⁺ or NADP⁺ as acceptor

                1.17.1.5 nicotinate dehydrogenase

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Results	in table
6	Activating Compound
1130	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
38	Cofactor
2	Crystallization (Commentary)
4	General Information
3	General Stability
22	Inhibitors
10	KM Value [mM]
5	Localization
2	Metals/Ions
25	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
29	Organism
2	Oxidation Stability
4	Pathway
11	pH Optimum
1	pH Range
3	pH Stability
4	Protein Variants
8	Purification (Commentary)
1	Reaction
9	Reaction Type
27	Reference
1	Renatured (Commentary)
2	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
58	Substrates and Products (Substrate)
13	Subunits
25	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Storage Stability

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Storage Stability on EC 1.17.1.5 - nicotinate dehydrogenase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C, increase of activity in crude extract

Neobacillus niacini

-

644533

room temperature, 50 mM Tris-HCl buffer, pH 8.2, after 1 day 40% loss of hydroxylase activity, after 7 days 62% loss of hydroxylase activity, NADPH oxidase and diaphorase activity of enzyme are more stable

Eubacterium barkeri

-

644535

room temperature, pH8, 9 days, 75% loss of hydroxylase activity

Eubacterium barkeri

-

644535