1.16.1.8: [methionine synthase] reductase

This is an abbreviated version!
For detailed information about [methionine synthase] reductase, go to the full flat file.

Word Map on EC 1.16.1.8

1.16.1.8

mthfr

folate

methylenetetrahydrofolate

case-control

gg

hyperhomocysteinemia

one-carbon

cystathionine

tetrahydrofolate

folic

remethylation

thymidylate

beta-synthase

transcobalamin

methylmalonic

megaloblastic

folate-related

spina

bifida

cobiialamin

methyltetrahydrofolate

cobalamin-dependent

homocystinuria

gcpii

diagnostics

t-hcys

medicine

folate-metabolizing

Reaction

2 [methionine synthase]-methylcob(III)alamin + 2 S-adenosyl-L-homocysteine +

= 2 [methionine synthase]-cob(II)alamin +

+ 2 S-adenosyl-L-methionine

Synonyms

EC 2.1.1.135, Methionine synthase cob(II)alamin reductase (methylating), Methionine synthase reductase, MSR, MTRR, NADPH-dependent diflavin oxidoreductase, Reductase, methionine synthase

ECTree

1 Oxidoreductases

1.16 Oxidizing metal ions

1.16.1 With NAD⁺ or NADP⁺ as acceptor

1.16.1.8 [methionine synthase] reductase

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Results	in table
1	Activating Compound
24	AA Sequence
5	Application
1	CAS Registry Number
8	Cloned(Commentary)
37	Cofactor
1	Crystallization (Commentary)
479	Disease/ Diagnostics
1	Expression
9	General Information
7	Inhibitors
12	Ki Value [mM]
21	KM Value [mM]
1	Localization
4	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
22	Organism
1	Pathway
2	PDB ID
5	pH Optimum
13	Protein Variants
3	Purification (Commentary)
4	Reaction
1	Reaction Type
20	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
29	Substrates and Products (Substrate)
7	Subunits
31	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
9	Turnover Number [1/s]

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0.43

2,6-dichlorophenolindophenol

Homo sapiens

Q9UBK8

variant I22/S175

657920

0.86

3-acetylpyridine adenine dinucleotide phosphate

Homo sapiens

Q9UBK8

variant I22/S175

657920

1.61

doxorubicin

Homo sapiens

Q9UBK8

variant I22/S175

657920

8.24

ferricyanide

Homo sapiens

Q9UBK8

variant I22/S175

657920

1.61

menadione

Homo sapiens

Q9UBK8

variant I22/S175

657920

3.6 - 7.8

NADPH

4 entries