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1.14.99.B5: 2-octaprenyl-6-methoxyphenol hydroxylase

This is an abbreviated version!
For detailed information about 2-octaprenyl-6-methoxyphenol hydroxylase, go to the full flat file.

Reaction

2-methoxy-6-(all-trans-octaprenyl)phenol
+
a reduced electron acceptor
+
oxygen
=
6-all-trans-octaprenyl-2-methoxy-1,4-benzoquinol
+
an oxidized electron acceptor
+
H2O

Synonyms

ubiH, visB

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.B5 2-octaprenyl-6-methoxyphenol hydroxylase

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Resultsin table
1AA Sequence
1Cloned(Commentary)
3General Information
1Organism
2Pathway
1Reaction
1Reference
1Substrates and Products (Substrate)
2Synonyms

Substrates Products

Substrates Products on EC 1.14.99.B5 - 2-octaprenyl-6-methoxyphenol hydroxylase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-methoxy-6-(all-trans-octaprenyl)phenol + a reduced electron acceptor + oxygen
6-all-trans-octaprenyl-2-methoxy-1,4-benzoquinol + a reduced electron acceptor + H2O
show the reaction diagram
no direct biochemical evidence for the enzymatic activity. Based on information obtained from studies with ubiquinone-deficient mutants, a pathway is proposed for ubiquinone biosynthesis in Escherichia coli. ubiH mutants accumulate small quantities of 2-octaprenyl-6-methoxyphenol and relatively large amounts of 2-octaprenylphenol
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