1.14.19.44: acyl-CoA (8-3)-desaturase
This is an abbreviated version!
For detailed information about acyl-CoA (8-3)-desaturase, go to the full flat file.
Word Map on EC 1.14.19.44
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1.14.19.44
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6-desaturase
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polyunsaturated
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phospholipid
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arachidonic
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linoleic
-
pufas
-
eicosapentaenoic
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5-desaturation
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omega
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desaturases
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docosahexaenoic
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dihomo-gamma-linolenic
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gamma-linolenic
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eicosatrienoic
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alpha-linolenic
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eicosa-8,11,14-trienoic
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coconut
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linoleoyl-coa
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linseed
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fat-free
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elongase
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safflower
- 1.14.19.44
-
6-desaturase
-
polyunsaturated
- phospholipid
-
arachidonic
-
linoleic
-
pufas
-
eicosapentaenoic
-
5-desaturation
- omega
-
desaturases
-
docosahexaenoic
-
dihomo-gamma-linolenic
-
gamma-linolenic
-
eicosatrienoic
-
alpha-linolenic
-
eicosa-8,11,14-trienoic
-
coconut
- linoleoyl-coa
-
linseed
-
fat-free
- elongase
- safflower
Reaction
+ 2 ferrocytochrome b5 + + 2 H+ = + 2 ferricytochrome b5 + 2 H2O
Synonyms
acyl-CoA 5-desaturase, acyl-CoA 5-desaturase (methylene-interrupted), D5D, DELTA 5-desaturase, delta-5 desaturase, DELTA5-desaturase, FADDELTA5, FADS1
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Reference
Reference on EC 1.14.19.44 - acyl-CoA (8-3)-desaturase
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Tripodi, K.E.; Buttigliero, L.V.; Altabe, S.G.; Uttaro, A.D.
Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan
FEBS J.
273
271-280
2006
Leishmania major, Leishmania major Friedlin
Tavares, S.; Grotkjaer, T.; Obsen, T.; Haslam, R.; Napier, J.; Gunnarsson, N.
Metabolic engineering of Saccharomyces cerevisiae for production of eicosapentaenoic acid, using a novel DELTA5-desaturase from Paramecium tetraurelia
Appl. Environ. Microbiol.
77
1854-1861
2011
Paramecium tetraurelia, Ostreococcus tauri, Ostreococcus sp. 'lucimarinus', Mortierella alpina (D5KSD5), Leishmania major (Q4QIH7), Mortierella alpina CBS 608.70 (D5KSD5)
Cho, H.; Nakamura, M.; Clarke, S.
Cloning, expression, and fatty acid regulation of the human DELTA-5 desaturase
J. Biol. Chem.
274
37335-37339
1999
Homo sapiens, Rattus norvegicus
Park, W.J.; Kothapalli, K.S.; Reardon, H.T.; Lawrence, P.; Qian, S.B.; Brenna, J.T.
A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids
J. Lipid Res.
53
1502-1512
2012
Homo sapiens, Papio anubis
Zhu, J.; Sun, Q.; Zong, G.; Si, Y.; Liu, C.; Qi, Q.; Ye, X.; Sun, L.; Sheng, H.; Li, H.; Lin, X.
Interaction between a common variant in FADS1 and erythrocyte polyunsaturated fatty acids on lipid profile in Chinese Hans
J. Lipid Res.
54
1477-1483
2013
Homo sapiens
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