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1.14.19.44: acyl-CoA (8-3)-desaturase

This is an abbreviated version!
For detailed information about acyl-CoA (8-3)-desaturase, go to the full flat file.

Word Map on EC 1.14.19.44

Reaction

(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
Arachidonoyl-CoA
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA 5-desaturase, acyl-CoA 5-desaturase (methylene-interrupted), D5D, DELTA 5-desaturase, delta-5 desaturase, DELTA5-desaturase, FADDELTA5, FADS1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.44 acyl-CoA (8-3)-desaturase

Natural Substrates Products

Natural Substrates Products on EC 1.14.19.44 - acyl-CoA (8-3)-desaturase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA + ferrocytochrome b5 + O2 + H+
arachidonoyl-CoA + ferricytochrome b5 + H2O
show the reaction diagram
(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + ferrocytochrome b5 + O2 + H+
(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoyl-CoA + ferricytochrome b5 + H2O
show the reaction diagram