1.14.19.44: acyl-CoA (8-3)-desaturase

This is an abbreviated version, for detailed information about acyl-CoA (8-3)-desaturase, go to the full flat file.

Reaction

(8Z,11Z,14Z)-icosa-8,11,14-trienoyl-CoA
+ 2 ferrocytochrome b5 +
O2
 + 2 H+ =
Arachidonoyl-CoA
 + 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA 5-desaturase, acyl-CoA 5-desaturase (methylene-interrupted), D5D, DELTA 5-desaturase, delta-5 desaturase, DELTA5-desaturase, FADDELTA5, FADS1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.44 acyl-CoA (8-3)-desaturase